Clinical trial · Interventional
Effects of Regional Nerve Block on Cancer Recurrence
NCT03134430CI-TRIAL-00033092unknownN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
It has been reported local anesthetics could inhibit tumor cell proliferation, metastasis and invasion ability，but it is still lack of clinical evidence. Our study aims to explore the effects of regional nerve block on cancer recurrence and the mechanism.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cancer Patient | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Normal saline | Other | — | UNRESOLVED |
| peripheral Nerve block | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- PLACEBO_COMPARATOR
- label
- Normal saline
- description
- equal volume of normal saline as treatment group
- interventionNames
- Other: Normal saline
- type
- ACTIVE_COMPARATOR
- label
- peripheral Nerve block
- description
- 0.35% ropivacaine and 0.5% lidocaine in normal saline
- interventionNames
- Other: peripheral Nerve block
Primary outcomes (1)
- measure
- the effect of nerve block on the cancer recurrence rate and survival rate postoperation
- timeFrame
- up to 5 years after surgery
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 80 Years
Show eligibility criteria text
Inclusion Criteria: * Patients with primary cancer undergoing elective surgery under general anesthesia Exclusion Criteria: * Disagree to participate，drop out,lose track, infectious abdominal wall，abnormal puncture point，coagulation dysfunction，allergy of local anesthetic ，immune disease,cancer metastasis,mental disease, acute and chronic infectious disease or other severe disease.
References
Publications (0)
Data not yet available
No reference posted for this study.