Clinical trial · Interventional
Oligo-metastases NPC Patients Received Radiation for Primary Tumors and Treatments for Metastatic Lesions
The Clinical Curative Efficacy and Side Effect of Oligo-metastases Nasopharyngeal Carcinoma Patients Received Radical Radiation for Primary Tumors and Treatments for Metastatic Lesions
NCT03129412CI-TRIAL-00047209unknownPhase 2ClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Oligo-metastases NPC patients received radiation for primary tumors and treatments for metastatic lesions.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Nasopharyngeal Cancer | Malignant Nasopharyngeal Neoplasm | CURATED_EXACT | 0.92 |
| Neoplasm Metastasis | Nasopharyngeal Neoplasm | PROBABILISTIC | 0.70 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| radical radiotherapy | Radiation | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- EXPERIMENTAL
- label
- Arm 1
- description
- 4-6 cycles chemotherapy and radical radiotherapy for primary tumors were given. Appropriate treatments for olio-metastatic lesions will assigned to those who got PR,SD after chemotherapy.
- interventionNames
- Radiation: radical radiotherapy
Primary outcomes (1)
- measure
- Overall survival
- timeFrame
- From date of diagnosis until the date of first documented progression or date of death from any cause, whichever came first, assessed up to 36 months
- description
- Events of death caused by any reasons
Secondary outcomes (1)
- measure
- Progress free survival
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 65 Years
Show eligibility criteria text
Inclusion Criteria: 1. Histologically conformed initial non-keratinizing squamous carcinoma in nasopharynx. 2. Clinical stages,T1-4N0-3M1，IVc(AJCC 2010). 3. The metastatic lesions ≤5 and metastatic organs ≤2 4. Karnofsky scores \>70 5. Normal hemodynamic indices before the recruitment (including white blood cell count\>4.0×109/L, neutrophil count\>1.5×109/L, platelet count \>100×109/L, hemoglobin≥90g/l, normal liver/kidney function). 6. Informed consent signed. Exclusion Criteria: 1. Histologically conformed initial keratinizing carcinoma or others. 2. The metastatic lesions \>5 or metastatic organs \>2. 3. Any severe complications contraindicated chemotherapy or radiotherapy. 4. History of malignant tumors. 5. Pregnant or nursing women. 6. History of radiotherapy or chemotherpy in head and neck regions. 7. Patients refused the informed consent.
References
Publications (0)
Data not yet available
No reference posted for this study.