Clinical trial · Interventional
Laparoscopic Total Gastrectomy With Versus Without Bursectomy
Laparoscopic Total Gastrectomy With Bursectomy in a Left Outside Bursa Omentalis Approach Versus Laparoscopic Total Gastrectomy Without Bursectomy for Advanced Posterior Gastric Wall Cancer: a Randomized Controlled Study
NCT03117283CI-TRIAL-00027028unknownPhase 2ClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Bursectomy is widely performed in open surgery for advanced gastric cancer in East Asia. However laparoscopic D2 radical total gastrectomy with complete bursectomy is difficult and rare performed. Herein, we conduct a single-centre randomized controlled trial to explore the safety and feasibility of totally laparoscopic D2 radical total gastrectomy using a left outside bursa omentalis approach for achieving complete bursectomy.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| A Left Outside Bursa Omentalis Approach | — | UNRESOLVED | — |
| Laparoscopic Bursectomy | — | UNRESOLVED | — |
| Laparoscopic Gastrectomy | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Laparoscopic D2 radical total gastrectomy with bursectomy using a left outside bursa omentalis approach | Procedure | — | UNRESOLVED |
| Laparoscopic D2 radical total gastrectomy without bursectomy | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- LTG with Bursectomy
- description
- laparoscopic D2 radical total gastrectomy with bursectomy using a left outside bursa omentalis approach
- interventionNames
- Procedure: Laparoscopic D2 radical total gastrectomy with bursectomy using a left outside bursa omentalis approach
- type
- SHAM_COMPARATOR
- label
- LTG without Bursectomy
- description
- laparoscopic D2 radical total gastrectomy without bursectomy
- interventionNames
- Procedure: Laparoscopic D2 radical total gastrectomy without bursectomy
Primary outcomes (1)
- measure
- Early morbidity
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 75 Years
Show eligibility criteria text
Inclusion Criteria: * Primary gastric adenocarcinoma diagnosed pathologically by endoscopic biopsy * Tumor located in the posterior wall of upper and middle third stomach estimated by endoscopy and CT scan * Informed consent * Eastern Cooperative Oncology Group (ECOG): 0 ot 1 * American Society of Anesthesiologists （ASA） score: Ⅰto Ⅲ Exclusion Criteria: * Pregnancy or female in suckling period * Contraindication to general anesthesia (severe cardiac and/or pulmonary disease) * Severe mental disease * Emergency operation due to complication (bleeding, perforation or obstruction) caused by primary tumor
References
Publications (8)
- RESULTHundahl SA. The potential value of bursectomy in operations for trans-serosal gastric adenocarcinoma. Gastric Cancer. 2012 Jan;15(1):3-4. doi: 10.1007/s10120-011-0121-6. No abstract available. PMID 22160297
- RESULTJapanese Gastric Cancer Association Registration Committee; Maruyama K, Kaminishi M, Hayashi K, Isobe Y, Honda I, Katai H, Arai K, Kodera Y, Nashimoto A. Gastric cancer treated in 1991 in Japan: data analysis of nationwide registry. Gastric Cancer. 2006;9(2):51-66. doi: 10.1007/s10120-006-0370-y. PMID 16767357
- RESULTFujita J, Kurokawa Y, Sugimoto T, Miyashiro I, Iijima S, Kimura Y, Takiguchi S, Fujiwara Y, Mori M, Doki Y. Survival benefit of bursectomy in patients with resectable gastric cancer: interim analysis results of a randomized controlled trial. Gastric Cancer. 2012 Jan;15(1):42-8. doi: 10.1007/s10120-011-0058-9. Epub 2011 May 15. PMID 21573917
- RESULTImamura H, Kurokawa Y, Kawada J, Tsujinaka T, Takiguchi S, Fujiwara Y, Mori M, Doki Y. Influence of bursectomy on operative morbidity and mortality after radical gastrectomy for gastric cancer: results of a randomized controlled trial. World J Surg. 2011 Mar;35(3):625-30. doi: 10.1007/s00268-010-0914-5. PMID 21161652
- RESULTKayaalp C, Piskin T, Olmez A. Complications of bursectomy after radical gastrectomy for gastric cancer. World J Surg. 2012 Jan;36(1):229; author reply 230. doi: 10.1007/s00268-011-1218-0. No abstract available. PMID 21833663
- RESULTHirao M, Kurokawa Y, Fujita J, Imamura H, Fujiwara Y, Kimura Y, Takiguchi S, Mori M, Doki Y; Osaka University Clinical Research Group for Gastroenterological Study. Long-term outcomes after prophylactic bursectomy in patients with resectable gastric cancer: Final analysis of a multicenter randomized controlled trial. Surgery. 2015 Jun;157(6):1099-105. doi: 10.1016/j.surg.2014.12.024. Epub 2015 Feb 20. PMID 25704429