Clinical trial · Interventional
Best Biliary Drainage Option in Advanced Klatskin Tumor
Best Biliary Drainage Option in Type II、III、IV Klatskin Tumor：ERCP or PTBD
NCT03104582CI-TRIAL-00039449completedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
To investigate the biliary drainage-related cholangitis and other complications of percutaneous transhepatic biliary drainage (PTBD) in the management of Klatskin tumor (KT) compared with endoscopic biliary drainage (EBD).
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cholangitis | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| ERCP Drainage | Procedure | — | UNRESOLVED |
| PTBD Drainage | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Biliary drainage 1
- description
- Patients with advanced hilar cholangiocarcinoma need biliary drainage performed Endoscopic Retrograde Cholangiopancreatography (ERCP) drainage
- interventionNames
- Procedure: ERCP Drainage
- type
- ACTIVE_COMPARATOR
- label
- Biliary drainage 2
- description
- Patients with advanced hilar cholangiocarcinoma need biliary drainage performed percutaneous transhepatic biliary drainage(PTBD) drainage
- interventionNames
- Procedure: PTBD Drainage
Primary outcomes (1)
- measure
- Acute cholangitis
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 90 Years
Show eligibility criteria text
Inclusion Criteria: * Type II、III、IV Klatskin tumor patients; * 18-90 years old Exclusion Criteria: * Unwillingness or inability to consent for the study; * Coagulation dysfunction (INR\> 1.3) and low peripheral blood platelet count(\<50×109 / L) or using anti-coagulation drugs; * Previous endoscopic sphincterectomy (EST) or endoscopic papillary balloon dilatation (EPBD); * Any type of GI reconstruction; * Combined with Mirizzi syndrome and intrahepatic bile duct stones; * Preoperative coexistent diseases: acute pancreatitis, GI tract hemorrhage, severe liver disease, primary sclerosing cholangitis (PSC), septic shock; * Biliary-duodenal fistula; * Pregnant women
References
Publications (1)
- DERIVEDBa Y, Yue P, Leung JW, Wang H, Lin Y, Bai B, Zhu X, Zhang L, Zhu K, Wang W, Meng W, Zhou W, Liu Y, Li X. Percutaneous transhepatic biliary drainage may be the preferred preoperative drainage method in hilar cholangiocarcinoma. Endosc Int Open. 2020 Feb;8(2):E203-E210. doi: 10.1055/a-0990-9114. Epub 2020 Jan 22. PMID 32010755