Clinical trial · Observational
Contrast-enhanced Ultrasound-guided Fine-needle Aspiration Biopsy in the Evaluation of Thyroid Nodules
Application Value of Contrast-enhanced Ultrasound-guided Fine-needle Aspiration Biopsy in the Evaluation of Thyroid Nodules
NCT03102099CI-TRIAL-00026798unknownClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
To evaluate the application value of contrast-enhanced ultrasound in the diagnosis of thyroid nodules using fine needle aspiration.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Thyroid Nodules | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| contrast-enhanced ultrasound group | Procedure | — | UNRESOLVED |
| conventional ultrasound group | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- label
- contrast-enhanced ultrasound group
- description
- The contrast-enhanced ultrasound(CEUS)patients will undergo biopsy with contrast-enhanced ultrasound guidance.
- interventionNames
- Procedure: contrast-enhanced ultrasound group
- label
- conventional ultrasound group
- description
- The conventional ultrasound group will undergo biopsy with conventional ultrasound guidance.
- interventionNames
- Procedure: conventional ultrasound group
Primary outcomes (1)
- measure
- The Bethesda System for Reporting Thyroid Cytology (TBSRTC)
- timeFrame
- From date of randomization until the date of first documented cytopathology result of fine needle aspiration (FNA) on the suspected nodule, assessed up to 1 month
- description
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Patients with a space-occupying thyroid lesion found either via conventional ultrasound or CT/MRI and clinically requiring a further biopsy. * Age 18 years old or above with no limitation of gender. * Obtain a signed informed consent. Exclusion Criteria: * Contraindications to the use of contrast agents as described by the medication guide. * Patients who are contraindicated to aspiration biopsy: patients with unexplained bleeding history, severe anemia, or patients who have a tendency to bleed and this bleeding disorder has not been corrected (prothrombin time 3-5seconds longer than the normal control, platelet count \<60000/mm3); no safe aspiration path; menstruating female patients. * If the patient has a serious psychological or mental problem, and is suspected to have a poor compliance with the current clinical study, or maybe unable to obtain a definitive diagnosis for the lesion. * Pregnant or lactating women or women with a positive pregnancy test before their first medications are given.
References
Publications (0)
Data not yet available
No reference posted for this study.