Clinical trial · Interventional
Frailty Evaluation in Elderly Population With Cancer
Exploratory Study of Frailty Evaluation in Elderly Population With Cancer
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The Comprehensive Geriatric Assessment (CGA) is, still today, barely established in the standard practice. Although the different scientific societies recommend a CGA in elderly population affected with cancer at first visit, the evidence regarding its transcendence is limited. On the other hand, the components of this evaluation and the translation of their findings in changes in the clinical practice are not stablished. This project intends to implement a CGA in a group of patients to compare this group with an historical cohort that reflects the standard practice, to evaluate the differences between both approaches. The study also evaluate the feasibility and utility of this CGA. All these questions aims to support the hypothesis that CGA impacts on the cancer treatment for elderly population affected with cancer.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cancer | Malignant Neoplasm | ALIAS | 0.90 |
| Fragility | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Comprehensive Geriatric Assessment (CGA) | Diagnostic Test | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- CASE ARM
- description
- This is a three cohorts arm with intervention (CGA): * Nutritional Assessment: Mini Nutritional Assessment (MNA) * Functional Assessment: Get up and Go, Activities of Daily Living (ADL), Instrumental Activities of Daily Living (IADL), Karnofsky Scale, Walking one Block, Number of Falls in last 6 months and Hearing Loss. * Cognitive Assessment: Mini-Mental State Examination (MMSE-30) * Psychological status: Geriatric Depression Scale (GDS) * Social Support: Medical Outcomes Study Social Support Survey (MOS-SSS) * Comorbidity and Severity of Comorbidities: Charlson Comorbidity Index and Adult Comorbidity Evaluation (ACE-27) * Age * Haemoglobin * Creatinine Clearance (CrCl) * Presence of Geriatric Syndromes
- interventionNames
- Diagnostic Test: Comprehensive Geriatric Assessment (CGA)
- type
- NO_INTERVENTION
- label
- CONTROL ARM
- description
- This is a three cohorts arm with no intervention
Primary outcomes (1)
- measure
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 70 Years
Show eligibility criteria text
Inclusion Criteria: * Age more than 70 years * Outpatients * Patients diagnosed with stage III colon cancer, stage IV colorectal cancer or stage IV NSCLC * No previous diagnosis of cancer. * No previous chemotherapy for current diagnosis of cancer * Signed informed consent Exclusion Criteria: * Not fulfilling inclusion criteria
References
Publications (0)
Data not yet available