Clinical trial · Interventional
Transverse Coloplasty vs. Side-to-end Anastomosis Following Low Anterior Resection (LAR): CSAR Trial
NCT03074461CI-TRIAL-00027948CSARunknownN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
CSAR Trial's aim is to determine whether the transverse coloplasty pouch or the side-to-end anastomosis as rectal reservoir reconstruction offers the best functional results.
Conditions
Conditions (4)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Fecal Incontinence | — | UNRESOLVED | — |
| Rectal Cancer | Malignant Rectal Neoplasm | CURATED_EXACT | 0.92 |
| Rectal Neoplasms | Rectal Neoplasm | ONTOLOGY_EXACT | 0.98 |
| Rectal Tumors | Rectal Neoplasm | ALIAS | 0.90 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Side-to-End Anastomosis | Procedure | — | UNRESOLVED |
| Transverse Coloplasty | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Side-to-End
- description
- Side-to-End Anastomosis as neorectal reconstruction technique in low anterior resection (LAR)
- interventionNames
- Procedure: Side-to-End Anastomosis
- type
- ACTIVE_COMPARATOR
- label
- Transverse Coloplasty
- description
- Transverse Coloplasty pouch as neorectal reconstruction technique in low anterior resection (LAR)
- interventionNames
- Procedure: Transverse Coloplasty
Primary outcomes (1)
- measure
- Stool frequency
- timeFrame
- time = 6 months postoperative
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Scheduled low anterior resection in patients with distal rectal carcinoma and planned anastomosis in mid/distal third of rectum * Local curative approach * Normal continence preoperatively * Non-IBD-associated carcinoma * Possible sphincter salvage * Signed informed consent Exclusion Criteria: * Non-curative approaches * Emergency surgery in cases of tumor perforation, abscess, sepsis * Proximal rectal carcinoma (\> 12 cm from anocutaneous line) * Lack of informed consent * Age \<18 years * Inclusion in other trials with interference of endpoints * Life expectancy less than 24 months (as estimated by the treating physicians) * Pregnancy * Immunosuppression
References
Publications (0)
Data not yet available
No reference posted for this study.