Clinical trial · Interventional
The Impact of Trimodal Prehabilitation Strategy on Patients Undergoing Thoracoscopic Lobectomy
The Impact of Trimodal Prehabilitation Strategy on Perioperative Functional Capability and Prognosis of Patients Undergoing Thoracoscopic Lobectomy for Lung Cancer：a Randomized Controlled Trail
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The process of enhancing an individual's functional capacity to optimize physiologic reserves before an operation to withstand the stress of surgery has been coined prehabilitation. This is a prospective randomized controlled trail, designed to explore if the patients who take thoracoscopic lobectomy for lung cancer will benefit from family trimodal prehabilitation strategy. Trimodal prehabilitation includes exercise, nutrition supplement and physiology management preoperatively. It starts from the day that patients decide to take the surgery until the day before surgery, lasting 2\~3 week in our hospital. And we follow-up patients until 8 weeks after surgery to investigate if trimodal prehabilitation strategy can improve the postoperative functional recovery，reduce complications and improve prognosis.
Conditions
Conditions (6)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Lobectomy | — | UNRESOLVED | — |
| Lung Cancer | Malignant Lung Neoplasm | CURATED_EXACT | 0.92 |
| Perioperative | — | UNRESOLVED | — |
| Prehabilitation | — | UNRESOLVED | — |
| Recovery | — | UNRESOLVED | — |
| Thoracoschisis | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Trimodal prehabilitation management | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Prehabilitation group
- description
- Trimodal prehabilitation management
- interventionNames
- Behavioral: Trimodal prehabilitation management
- type
- NO_INTERVENTION
- label
- Control group
- description
- The patients will receive the conventional clinical guidance according to Peking Union Medical College Hospital, including preoperative anesthesia assessment, drug treatment recommendations for chronic disease, quit smoking and abstinence.
Primary outcomes (1)
- measure
- 6-minute-walking-distance (6MWD)
- timeFrame
- 4 weeks postoperatively
- description
- Use 6-minute-walking-distance (6MWD) to evaluate the physical functional capability objectively.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 70 Years
Show eligibility criteria text
Inclusion Criteria: 1. Outpatient of thoracic surgery department in Peking Union Medical College Hospital 2. From 18 y/o to 70 y/o 3. Suspected of lung cancer 4. Decide to take the elective thoracoscopic surgery in Peking Union Medical College Hospital Exclusion Criteria: 1. Refuse or fail to cooperate the study (due to any reason) 2. ASA grade ≥ III 3. Unable to tolerate prehabilitaion strategy (including exercise guide, whey protein and psycho-relaxation exercise) 4. Other severe cardio-pulmonary diseases that would affect the 6MWD
References
Publications (1)
- DERIVEDLiu Z, Qiu T, Pei L, Zhang Y, Xu L, Cui Y, Liang N, Li S, Chen W, Huang Y. Two-Week Multimodal Prehabilitation Program Improves Perioperative Functional Capability in Patients Undergoing Thoracoscopic Lobectomy for Lung Cancer: A Randomized Controlled Trial. Anesth Analg. 2020 Sep;131(3):840-849. doi: 10.1213/ANE.0000000000004342. PMID 31348053