Clinical trial · Interventional
Colorectal Polyps Screening With Low-dose CT Colonoscopy
Colorectal Adenoma Screening by Low-dose CT Colonoscopy With Computer-aided Detection
NCT03064828CI-TRIAL-00033892unknownN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This preliminary clinical trial aims to evaluate the performance of the low-dose CT colonoscopy (CTC) with computer aided detection (CAD) on polyps detection compared with optical colonoscopy (OC), and explore the possible clinical routine for integrated use of CT colonoscopy and optical colonoscopy OC in colorectal cancer screening.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Colorectal Neoplasm | Colorectal Neoplasm | ONTOLOGY_EXACT | 0.98 |
| Polyps | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| CT colonoscopy (low dose) | Radiation | — | UNRESOLVED |
| CT colonoscopy(normal dose) | Radiation | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- ACTIVE_COMPARATOR
- label
- CT colonoscopy(normal dose)
- description
- Perform CT colonoscopy with full bowel preparation and inflated colon, CT Scans on subjects with normal-dose protocol by setting scanning parameters as 120-140 kilovolts peak (kVp), 100-200mA
- interventionNames
- Radiation: CT colonoscopy(normal dose)
- type
- EXPERIMENTAL
- label
- CT colonoscopy(low dose)
- description
- Perform CT colonoscopy with full bowel preparation and inflated colon, CT Scans on subjects with normal-dose protocol by setting scanning parameters as 120-140 kVp, 20-100mA
- interventionNames
- Radiation: CT colonoscopy (low dose)
Primary outcomes (1)
- measure
- Sensitivity and specificity of low-dose CTC for the polyp detection
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 70 Years
Show eligibility criteria text
Inclusion Criteria: * Subjects with gastrointestinal symptoms potentially suggestive of colorectal cancer, such as diarrhea, constipation, abdominal pain or discomfort, rectal bleeding, iron-deficiency anemia, and unintended weight loss. * Subjects with pathological confirmed colorectal cancer or polyps that need follow-up examination. * Subjects with written consents Exclusion Criteria: * Subjects with acute colitis * Acute diverticulitis * Inguinal hernia including colon * Colorectal surgery or endoscopic biopsy or resection of polyps within 6 months * Known or suspected as colon perforated * Complete intestinal obstruction * Pregnant or lactating women
References
Publications (0)
Data not yet available
No reference posted for this study.