Clinical trial · Interventional
Radiofrequency and Chemical Neurolysis of Thoracic Splanchnic Nerve for Abdominal Cancer Pain
Comparative Study Between Radiofrequency Thermocoagulation and Chemical Neurolysis of Thoracic Splanchnic Nerve Bilaterally for the Management of Abdominal Cancer Pain
NCT03063112CI-TRIAL-00026184RFunknownN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The study compares between the efficacy, safety and impact on the quality of life of radiofrequency thermocoagulation and chemical neurolysis of bilateral thoracic splanchnic nerves in the management of refractory pain which developed in patients suffering from upper abdominal cancer.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Abdominal Cancer | Malignant Abdominal Neoplasm | ALIAS | 0.90 |
Interventions
Interventions (4)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| C arm fluoroscopic device | Device | — | UNRESOLVED |
| Ethyl alcohol | Drug | — | UNRESOLVED |
| Lidocaine | Drug | — | UNRESOLVED |
| Radiofrequency generator device | Device | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- ACTIVE_COMPARATOR
- label
- Group 1( radiofrequency group )
- description
- Bilateral thoracic splanchnic nerves block will be performed by radiofrequency thermocoagulation at two level of vertebra T10 and T11 by using radiofrequency generator device and lidocaine 2% before thermal lesion
- interventionNames
- Device: Radiofrequency generator device
- Drug: Lidocaine
- type
- PLACEBO_COMPARATOR
- label
- Group 2 ( alcohol group )
- description
- Bilateral thoracic splanchnic nerves block will be performed by ethyl alcohol at one level of vertebraT11 by using of C arm fluoroscopic device.
- interventionNames
- Device: C arm fluoroscopic device
- Drug: Ethyl alcohol
Primary outcomes (1)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 70 Years
Show eligibility criteria text
Inclusion Criteria: 1. Patients suffering from upper abdominal cancer pain. 2. Visceral pain with visual analogue pain score ≥ 4. 3. Normal coagulation profile. 4. Positive diagnostic test. 5. Written informed consent from the patients . Exclusion Criteria: 1. Patients with organ failure. 2. Coagulation disorders. 3. Local infection at the puncture site or sepsis. 4. Allergy to the contrast dye or alcohol. 5. Severe displacement of intra-abdominal structures. 6. Pregnant women. 7. Documented metastatic lesions. 8. Psychiatric illness affecting cooperation. 9. De-compensated cardiac disorders. 10. Liver and renal dysfunction.
References
Publications (0)
Data not yet available
No reference posted for this study.