Clinical trial · Observational
Effects of Urinary Bladder Hypertrophy on Urge Urine Incontinence After Radical Prostatectomy
Could Urinary Bladder Hypertrophy Influence on Urge Urine Incontinence Development in Patients After Radical Prostatectomy: A Multi-center Study
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This study is designed to evaluate men before radical prostatectomy for the incidence of Overactive Bladder (OAB), as well as urge urine incontinence (UUI) development after the surgery. Patients will be evaluated for signs of OAB and for signs of Bladder Outlet Obstruction (BOO). Afterwards they will be divided into four observational groups. Follow up period is designed to be 12 months.
Conditions
Conditions (5)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Incontinence | — | UNRESOLVED | — |
| Overactive Bladder | — | UNRESOLVED | — |
| Prostate Cancer | Malignant Prostate Neoplasm | CURATED_EXACT | 0.92 |
| Prostatectomy | — | UNRESOLVED | — |
| Urinary Incontinence, Urge | — | UNRESOLVED | — |
Interventions
Interventions (3)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Evaluation after 1,3,6,9,12 months | Diagnostic Test | — | UNRESOLVED |
| Initial evaluation | Diagnostic Test | — | UNRESOLVED |
| Radical prostatectomy | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (5)
- label
- 1. OAB (-) BOO (-)
- description
- Patients diagnosed with prostate cancer, undergoing radical prostatectomy, with no overactive bladder (OAB) symptoms and without bladder outlet obstruction (BOO). 'Initial evaluation' before the surgery and follow up - 'Evaluation after 1,3,6,9,12 months'.
- interventionNames
- Procedure: Radical prostatectomy
- Diagnostic Test: Initial evaluation
- Diagnostic Test: Evaluation after 1,3,6,9,12 months
- label
- 2. OAB (-) BOO (+)
- description
- Patients diagnosed with prostate cancer, undergoing radical prostatectomy, with no overactive bladder (OAB) symptoms and with bladder outlet obstruction (BOO). 'Initial evaluation' before the surgery and follow up - 'Evaluation after 1,3,6,9,12 months'.
- interventionNames
- Procedure: Radical prostatectomy
- Diagnostic Test: Initial evaluation
- Diagnostic Test: Evaluation after 1,3,6,9,12 months
- label
- 3. OAB (+) BOO (+)
Eligibility
Eligibility (as posted)
- Sex
- Male
- Minimum age
- 40 Years
Show eligibility criteria text
Inclusion Criteria: * Adult men over 40 years old with prostate cancer qualified for radical prostatectomy * Control group formed from 20 healthy men aged 20-40 years old without any urological conditions and no lower urinary tract symptoms (LUTS). Exclusion Criteria: * Neoadjuvant (any time before) or adjuvant radiotherapy or brachytherapy (within the follow-up period of 12 months). * Macroscopic infiltration of the bladder (pT4). * Neurological deficiencies, such as stroke, spinal cord injury, multiple sclerosis etc. causing inability to have any control of the bladder. * Urethral strictures. * Transurethral resection of the prostate or Adenomectomy performed within 12 months prior to Radical Prostatectomy. * Any form of constant catheterisation (indwelling catheter, clean intermittent catheterisation).
References
Publications (0)
Data not yet available