Clinical trial · Interventional
Ultrasound-guided Percutaneous Microwave Ablation for Benign Thyroid Nodules
NCT03057925CI-TRIAL-00028195unknownN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Percutaneous microwave ablation(MWA) was reported as an effective modality for the management of thyroid nodules(TNs). This study aims to validate MWA as a feasible approach for patients with TNs for whom surgery is contraindicated or refused. Two groups of subjects with TNs(one group to treat with MWA and the other group to receive regular ultrasonic follow-up without any treatment) will be evaluated in term of TN volume, ultrasonic image and clinical symptoms.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Thyroid Nodule | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Microwave Ablation | Device | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Group A
- description
- MWA Percutaneous Microwave Ablation intervention procedure: Ultrasound-guided Percutaneous Microwave Ablation
- interventionNames
- Device: Microwave Ablation
- type
- NO_INTERVENTION
- label
- Group B
- description
- untreated no treatment; regular ultrasonic image follow-up
Primary outcomes (1)
- measure
- Change of the thyroid nodule volume assessed by ultrasonography after treatment vs simple clinical observation
- timeFrame
- From time to treatment until 12 months. Time point evaluations at 1,3,6,12 months
- description
- Change of the thyroid nodule volume assessed by using ultrasonography, the volume reduction ratio(VRR) was calculated by the equation: VRR%=\[(initial volume-final volume)\*100\]/initial volume
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 70 Years
Show eligibility criteria text
Inclusion Criteria: * age\>18 years * benign thyroid nodules(TYP 2) * solid or predominantly solid(colloid component\<30%)large (\>3.0ml) thyroid nodules * refusal and/or inefficacy of surgery Exclusion Criteria: * pregnancy * malignant or suspicious thyroid nodules
References
Publications (1)
- DERIVEDWu W, Gong X, Zhou Q, Chen X, Chen X. Ultrasound-Guided Percutaneous Microwave Ablation for Solid Benign Thyroid Nodules: Comparison of MWA versus Control Group. Int J Endocrinol. 2017;2017:9724090. doi: 10.1155/2017/9724090. Epub 2017 Nov 23. PMID 29333159