Clinical trial · Interventional
Tailored Exercise Interventions to Reduce Fatigue in Cancer Survivors
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Cancer-related fatigue (CRF) is a common and distressing symptom of cancer and/or cancer treatment that can persist for months or years in cancer survivors. Exercise is beneficial for the management of CRF, and general exercise guidelines for cancer survivors are available. However, exercise interventions have not been tailored to alleviate CRF in fatigued cancer survivors, and thus the potential to alleviate CRF may not have been realized. The primary aim of this research is to investigate the effect of a traditional vs. tailored 12-week exercise intervention on self-reported CRF severity.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cancer-related Fatigue | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Tailored Exercise | Other | — | UNRESOLVED |
| Traditional Exercise | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- ACTIVE_COMPARATOR
- label
- Traditional Exercise
- description
- A classical exercise intervention based on current guidelines for cancer survivors.
- interventionNames
- Other: Traditional Exercise
- type
- EXPERIMENTAL
- label
- Tailored Exercise
- description
- A tailored and individualized exercise intervention based on the results of pre-intervention testing.
- interventionNames
- Other: Tailored Exercise
Primary outcomes (1)
- measure
- Assessment of change in the Functional Assessment of Chronic Illness Therapy - Fatigue (FACIT-Fatigue) Scale
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 75 Years
Show eligibility criteria text
Inclusion Criteria: * Aged between 18 and 75 years; * Functional Assessment of Chronic Illness Therapy-Fatigue (FACIT-Fatigue) score ≤ 34; * Completion of treatment in ≥ 3 months and ≤ 5 years preceding enrollment; * Approval received from personal physician and/or a Canadian Society for Exercise Physiology-Clinical Exercise Physiologist (CSEP-CEP); * Command of the English language. Exclusion Criteria: * Contraindication to experimental procedures including transcranial magnetic stimulation (TMS); * Diagnosed as having obstructive sleep apnea or anemia; * Currently participating in a structured exercise intervention; * Participant is pregnant.
References
Publications (1)
- DERIVEDTwomey R, Martin T, Temesi J, Culos-Reed SN, Millet GY. Tailored exercise interventions to reduce fatigue in cancer survivors: study protocol of a randomized controlled trial. BMC Cancer. 2018 Jul 24;18(1):757. doi: 10.1186/s12885-018-4668-z. PMID 30041626