Clinical trial · Observational
Surveillance Study for Early Detection of Cholangiocarcinoma (CCA) in Primary Sclerosing Cholangitis (PSC)
NCT03041662CI-TRIAL-00053909PSCcompletedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This observational study of a national cohort of 600 Swedish PSC patients include yearly MR/MRCP, biobanking of serum, plasma and blood, followup clinical data (interventions, symptoms, labs, colonoscopy). The aim is to collect a well characterized cohort of PSC patients and provide future possibilities to evaluate biomarkers for prognosis and early cancer detection.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cholangiocarcinoma | Cholangiocarcinoma | ONTOLOGY_EXACT | 0.98 |
| Primary Sclerosing Cholangitis | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| MR/MRCP | Diagnostic Test | — | UNRESOLVED |
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (3)
- measure
- cholangiocarcinoma
- timeFrame
- 10 yrs f-up
- description
- cholangiocarcinoma
- measure
- liver transplatation
- timeFrame
- 10 yrs f-up
- description
- liver transplatation
- measure
- death
- timeFrame
- 10 yrs f-up
- description
- death
Secondary outcomes (1)
- measure
- biliary dysplasia
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Diagnosis of PSC by MR/MRCP * Life expectancy \>1 year * Informed consent Exclusion Criteria: * Liver transplantation or on the waiting list * Secondry SC * Diagnosis of CCA
References
Publications (0)
Data not yet available
No reference posted for this study.