Clinical trial · Observational
Vitamin D Receptor Polymorphisms and Non-Melanoma Skin Cancer Risk
Vitamin D Receptor Polymorphisms and Non-Melanoma Skin Cancer Risks in Alabama Population
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of this study is to discover whether certain Vitamin D Receptor (VDR) gene polymorphisms are associated with an increased risk of cutaneous basal cell carcinoma (BCC) and/or cutaneous squamous cell carcinoma (SCC) in an Alabama population. Participant demographic information such as physical characteristics (e.g., ethnicity), family history, and cancer diagnosis will be collected in order to determine if there are relationships between the gene polymorphisms, cancer diagnosis, and these characteristics.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Skin Cancer, Non-Melanoma | Skin Carcinoma | ALIAS | 0.90 |
Interventions
Interventions (0)
Data not yet available
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (1)
- measure
- SIngle nucleotide polymorphisms (SNP)
- timeFrame
- 2 years
- description
- Number of patients with the presence or absence of VDR SNP in their DNA isolated from their blood samples. PCR will be performed on the DNA samples for using specific primers for SNP, and the PCR products will be sequenced for detection of SNP.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 50 Years
Show eligibility criteria text
Inclusion Criteria: * Patients with non-melanoma skin cancer (cases) * Patients without non-melanoma skin cancer or history of non-melanoma skin cancer (controls) * Age 50 and older * Native English speakers * Patients at Kirklin Clinic Exclusion Criteria: * Age less than 50 * Diagnosis of melanoma or other type of cancer * Non-English speakers
References
Publications (0)
Data not yet available