Clinical trial · Observational
Assessing How Normal Variations in CT Scanning Affects Its Interpretation
Stability of Radiomic Features for Abdominal Tumors on Contrast Enhanced CT
NCT03038568CI-TRIAL-00109066active not recruitingClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of the study is to see how measurements of tumor differences vary with slight changes in CT scan parameters. Reproducible radiomic features can be extracted for abdominal tumors, and specifically colorectal liver metastases, imaged with clinical CT scanners even in the setting of variable scan parameters and variable contrast timing. Participants will be consented to undergo an additional CT of their abdomen.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Colorectal Cancer Metastatic | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| CT scan | Diagnostic Test | — | UNRESOLVED |
Design
Arms and outcomes
Arms (18)
- label
- Cohort 1
- description
- -15 second time gap between routine abdominal CT and add on CT, Noise Index of 12
- interventionNames
- Diagnostic Test: CT scan
- label
- Cohort 2
- description
- -15 second time gap between routine abdominal CT and add on CT, Noise Index of 14
- interventionNames
- Diagnostic Test: CT scan
- label
- Cohort 3
- description
- -15 second time gap between routine abdominal CT and add on CT, Noise Index of 16
- interventionNames
- Diagnostic Test: CT scan
- label
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Patients ≥ 18 years of age on the day of signed informed consent * Patients scheduled and approved for contrast enhanced CT that includes imaging of the abdomen and pelvis following the Department of Radiology standard of care protocol as per local institutional guidelines * Patients with measurable colorectal liver metastases on prior imaging, with at least one tumor greater than 2.0 cm in axial maximal diameter Exclusion Criteria: * Patient who is pregnant and/or lactating * Patient scheduled for CT that includes the abdomen with a multiphasic contrast enhanced protocol (e.g. Triple Phase or Quadruple Phase Liver CT) * Patient who require reduced intravenous contrast dose based on the Department of Radiology contrast policy as per local institutional guidelines * Any other medical condition, including mental illness or substance abuse, deemed by the Investigator to be likely to interfere with a patient's ability to sign informed consent, cooperate and participate in the study, or follow up procedures
References
Publications (0)
Data not yet available
No reference posted for this study.