Clinical trial · Interventional
Efficacy of Oral Moisturizing Jelly on Oral Health and Nutrition in Post-radiotherapy Head and Neck Cancer Patients
A Randomized Controlled Trial for Efficacy of Oral Moisturizing Jelly on Oral Health and Nutrition in Post-radiotherapy Head and Neck Cancer Patients With Xerostomia
NCT03035825CI-TRIAL-00036994completedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This randomized control trial aims to investigate the efficacy of oral moisturizing jelly in head and neck cancer patients with xerostomia.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cancer of Head Neck | — | UNRESOLVED | — |
| Dry Mouth | — | UNRESOLVED | — |
| Radiation-Induced Xerostomia | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Artificial saliva | Other | — | UNRESOLVED |
| Oral moisturizing jelly | Dietary Supplement | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Oral Moisturizing Jelly
- description
- Daily intake of oral moisturizing jelly 5 times/day for two months
- interventionNames
- Dietary Supplement: Oral moisturizing jelly
- type
- ACTIVE_COMPARATOR
- label
- Artificial saliva
- description
- Daily use of non-edible oral lubricating gel 5 times/day for two months
- interventionNames
- Other: Artificial saliva
Primary outcomes (1)
- measure
- Changes in subjective dry mouth score compared to baseline
- timeFrame
- Baseline, 1 and 2 months after intervention
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 20 Years
Show eligibility criteria text
Inclusion Criteria: 1. Xerostomic head and neck cancer patients who finish radiotherapy for at least 1 month. 2. If undergoing chemotherapy, have to finish for at least 2 weeks. 3. Have subjective dry mouth scores at least 3 4. Can perform oral intake without aspiration 5. Can communicate well Exclusion Criteria: 1. Has recurrence of cancer 2. Has mucositis more than grade 1 3. Has oral infection such as candidiasis
References
Publications (2)
- DERIVEDLam-Ubol A, Matangkasombut O, Trachootham D, Tarapan S, Sattabanasuk V, Talungchit S, Paemuang W, Phonyiam T, Chokchaitam O, Mungkung OO. Efficacy of gel-based artificial saliva on Candida colonization and saliva properties in xerostomic post-radiotherapy head and neck cancer patients: a randomized controlled trial. Clin Oral Investig. 2021 Apr;25(4):1815-1827. doi: 10.1007/s00784-020-03484-1. Epub 2020 Aug 10. PMID 32779011
- DERIVEDNuchit S, Lam-Ubol A, Paemuang W, Talungchit S, Chokchaitam O, Mungkung OO, Pongcharoen T, Trachootham D. Alleviation of dry mouth by saliva substitutes improved swallowing ability and clinical nutritional status of post-radiotherapy head and neck cancer patients: a randomized controlled trial. Support Care Cancer. 2020 Jun;28(6):2817-2828. doi: 10.1007/s00520-019-05132-1. Epub 2019 Nov 15. PMID 31732852