Clinical trial · Interventional
Study of 1cm Versus 2cm Margins for the Surgical Treatment of cT2N0M0 Melanoma
Pilot Study of 1cm Versus 2cm Margins for the Surgical Treatment of cT2N0M0 Melanoma
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This is a randomized non-blinded pilot study for patients with melanoma staging cT2N0M0 who are candidates for surgical resection. The primary objective is to determine the feasibility of randomizing participants with cT2N0M0 malignant melanoma to surgical treatment with 1cm versus 2cm margins. Study will try to determine overall survival for cT2N0M0 malignant melanoma after surgical treatment with 1cm versus 2cm margins.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Malignant Melanoma | Melanoma | ALIAS | 0.90 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Wide Local Excision | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- OTHER
- label
- Wide Local Excision 1cm
- interventionNames
- Procedure: Wide Local Excision
- type
- OTHER
- label
- Wide Local Excision 2cm
- interventionNames
- Procedure: Wide Local Excision
Primary outcomes (1)
- measure
- Number of participants who agree to blinded randomization to a surgical margin trial for the treatment of early stage melanoma.
- timeFrame
- 2 years
- description
- Number of patients who agree to participate
Secondary outcomes (2)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Biopsy proven T2 malignant melanoma. * Eastern Cooperative Oncology Group (ECOG) score of 0-2. Exclusion Criteria: * Visible additional disease that suggests a greater than T2 malignant melanoma * Unable to tolerate general anesthesia * Evidence of distant metastatic disease * Melanoma located on face or digits
References
Publications (0)
Data not yet available