Clinical trial · Interventional
PixelShine vs. Iterative Reconstruction (IR) Processing of CT Images
Prospective Review of CT Imaging Data Comparing Quality of Low-Radiation-Dose Images Post-Processed With Iterative Reconstruction Software vs. Machine Learning (AlgoMedica PixelShine) Software
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This study will compare the quality of CT images acquired with very low-dose radiation and processed with commercially available software vs. PixelShine processed images. It would potentially allow imaging facilities to acquire CT scans using lower doses of radiation without sacrificing clarity of CT images. Acquiring high quality CT images with low-dose radiation has the potential to enhance patient safety and has significant implications in imaging practices.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cancer Liver | — | UNRESOLVED | — |
| Cancer, Lung | Malignant Lung Neoplasm | CURATED_EXACT | 0.92 |
| X-rays; Effects | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Conventional processing | Device | — | UNRESOLVED |
| PixelShine | Device | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- ACTIVE_COMPARATOR
- label
- Chest CT
- description
- Conventional processing vs. PixelShine processing
- interventionNames
- Device: PixelShine
- Device: Conventional processing
- type
- ACTIVE_COMPARATOR
- label
- Abdominal CT
- description
- Conventional processing vs. PixelShine processing
- interventionNames
- Device: PixelShine
- Device: Conventional processing
Primary outcomes (1)
- measure
- Visual Image Quality as Assessed by Image Noise Reduction
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Patients must be 18 years of age or older * Patients must be able and willing to consent to participate in this project * Patients will be scheduled for a standard of care CT scan Exclusion Criteria: * This study does not investigate either a specific disease or a specific patient population-it only examines and compares images obtained at low radiation exposure post-processed with Algomedica's PixelShine software with conventionally processed images * All other patients will be excluded
References
Publications (0)
Data not yet available