Clinical trial · Interventional
Effects of PEEP on Intracranial and Intraocular Pressure in Robot-assisted Laparoscopic Radical Prostatectomy
Effects of Positive End Expiratory Pressure (PEEP) on Intracranial and Intraocular Pressure in Robot-assisted Laparoscopic Radical Prostatectomy
NCT03031613CI-TRIAL-00025632unknownN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
To investigate the effects of positive end-expiratory pressure (PEEP) on the intracerebral pressure (ICP) and intraocular pressure (IOP) in patients undergoing robot assisted laparoscopic radical prostatectomy (RALRP)
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Prostate Cancer | Malignant Prostate Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| PEEP group | Procedure | — | UNRESOLVED |
| ZEEP group | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- PEEP group
- description
- Application of 5 cmH2O PEEP during mechanical ventilation
- interventionNames
- Procedure: PEEP group
- type
- ACTIVE_COMPARATOR
- label
- ZEEP group
- description
- No application of PEEP during mechanical ventilation
- interventionNames
- Procedure: ZEEP group
Primary outcomes (2)
- measure
- IOP
- timeFrame
- Changes from pre-induction (baseline) at Post-induction 5 min, Pneumoperitoneum insufflation and Trendelenburg position 5 min, Pneumoperitoneum insufflation and Trendelenburg position 30 min, Penumoperitoneum desufflation and supine position 5 min
Eligibility
Eligibility (as posted)
- Sex
- Male
Show eligibility criteria text
Inclusion Criteria: * Patients undergoing robotic-assisted laparoscopic radical prostatectomy Exclusion Criteria: * History of opthalmic disease or surgery * History of brain disease or surgery * Known ICP elevation * Known IOP elevation * Presence of lung bullae on chest x-ray * History of pneumothorax
References
Publications (0)
Data not yet available
No reference posted for this study.