Clinical trial · Interventional
EGFR Molecular Classification In Vivo
Molecular Imaging to Identify EGFR-TKIs Benefit Non-small Cell Lung Carcinoma Patients
NCT03031522CI-TRIAL-00043555completedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The investigators developed 18F-IRS as a targeted molecular imaging agent for noninvasive and repeatable detecting EGFR-activating mutational status.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Molecular Imaging | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| 18F-IRS | Radiation | — | UNRESOLVED |
Design
Arms and outcomes
Arms (6)
- type
- EXPERIMENTAL
- label
- 18F-IRS : EGFR+ Patients
- description
- Patients in this group had EGFR-activating mutant tumors and did not receive any treatment before this study.
- interventionNames
- Radiation: 18F-IRS
- type
- EXPERIMENTAL
- label
- 18F-IRS :post-TKI EGFR+ Patients
- description
- Patients with EGFR-activating mutant tumors were receiving EGFR-TKIs during this study .
- interventionNames
- Radiation: 18F-IRS
- type
- EXPERIMENTAL
- label
- 18F-IRS:post-chemo EGFR+
- description
- 18F-IRS:post-chemo EGFR+ Patients with EGFR-activating mutant tumors were receiving chemotherapy during this study.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 75 Years
Show eligibility criteria text
Inclusion Criteria: * Advanced NSCLC * 18 years or older * A life expectancy of at least 12 weeks * Presence of a malignant lesion within the chest of at least 0.5 cm diameter as measured by computed tomography (CT) * Written informed consent Exclusion Criteria: * Claustrophobia * Pregnancy * Metal implants in the thorax
References
Publications (0)
Data not yet available
No reference posted for this study.