Clinical trial · Interventional
BOND Study: the Benefit Of Night Splinting in Dupuytrens'
The Effectiveness of Night Splinting After Collagenase Injection for Dupuytren's Contracture
NCT03031080CI-TRIAL-00054100BONDwithdrawnN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Why stopped (as posted): Intervention (Xiapex) was removed from the market
Summary
Brief summary (as posted)
The BOND study is a prospective, randomised single blinded controlled trial to assess the effect of night splinting in patients who have had collagenase injection and manipulation therapy for Dupuytren's Contracture.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Dupuytren Contracture | Palmar Fibromatosis | ALIAS | 0.90 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Thermoplastic Hand Splint | Device | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- ACTIVE_COMPARATOR
- label
- Splinted
- description
- Patients will be given Thermoplastic Hand Splint to wear overnight for 12 weeks.
- interventionNames
- Device: Thermoplastic Hand Splint
- type
- NO_INTERVENTION
- label
- Un-Splinted
- description
- Patients will not wear a night splint
Primary outcomes (1)
- measure
- Range of motion
- timeFrame
- At 0 weeks, 12 weeks and 52 weeks
- description
- To assess change in range of motion measured in degrees between pre-treatment, immediately post-treatment, 12 weeks post-treatment and 12 months post-treatment
Eligibility
Eligibility (as posted)
- Sex
- All
Show eligibility criteria text
Inclusion Criteria: 1. Single digit contractures greater than 30 degrees 2. No prior surgery for their contractures. 3. Successful collagenase and manipulation therapy (contracture reduced to within 10 degrees of full extension). Exclusion Criteria: 1. Multiple digit contractures 2. Prior surgery for their contractures. 3. Failure of collagenase and manipulation therapy (contracture not reduced to within 10 degrees of full extension). 4. Inability to consent to treatment.
References
Publications (0)
Data not yet available
No reference posted for this study.