Clinical trial · Interventional
Skeletal Muscle Energy Metabolism in Women With Weight Loss and Ovarian and/or Endometrial Cancer With Weight Loss
Study of Differences in Skeletal Muscle Energy Metabolism Alterations in Women With Weight Loss and Ovarian and/or Endometrial Cancer Based on the Body Mass Index
NCT03027479CI-TRIAL-00099455METERMUS-IMCcompletedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
the aim is to study skeletal muscle metabolism alterations métaboliques associated with weight loss in women with ovarian and/or endometrial cancer according to BMI.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Endometrial Carcinoma | Endometrial Carcinoma | ONTOLOGY_EXACT | 0.98 |
| Ovarian Carcinoma | Ovarian Carcinoma | ONTOLOGY_EXACT | 0.98 |
| Weight Loss | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Samples | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Case group
- description
- women with ovarian and/or endometrial cancer and weight loss will have muscle, adipose tissue, ovarian tumor and blood samples
- interventionNames
- Other: Samples
- type
- OTHER
- label
- Control group
- description
- women scheduled for an intervention for benign ovarian/ endometrial disease and no weight loss will have muscle, adipose tissue and blood samples
- interventionNames
- Other: Samples
Primary outcomes (1)
- measure
- Measurement of muscle mitochondrial bioenergetics according to BMI
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
Show eligibility criteria text
Case group selection criteria: Inclusion Criteria: * Women aged 18 years old and more * Ovarian and/or endometrial cancer * weight loss related to cancer (weight loss \> 5% weight in one month or 10% in 6 months) * Indication to therapeutic surgery * Women affiliated to social security scheme * Women who can understand French and able to sign Informed consent Exclusion Criteria: * Unbalanced Diabetes * Chronic neuromuscular disorder * Any severe uncontrolled medical condition Control group selection criteria: Inclusion Criteria: * Women aged 18 years and more * Surgery Indication for a benign endometrial and/ or ovarian disease * Patient affiliated to social security scheme * Women who can understand French and able to sign Informed consent Exclusion Criteria: * Unbalanced Diabetes * Chronic neuromuscular disorder * Any severe uncontrolled medical condition
References
Publications (1)
- RESULTSalaun H, Poisson M, Dolly A, Arbion F, Servais S, Dumas JF, Goupille C, Ouldamer L. Total Polyunsaturated Fatty Acid Level in Abdominal Adipose Tissue as an Independent Predictor of Recurrence-Free Survival in Women with Ovarian Cancer. Int J Mol Sci. 2023 Jan 16;24(2):1768. doi: 10.3390/ijms24021768. PMID 36675280