Clinical trial · Interventional
Needle Guiding Robot for Radiofrequency Ablation: Safety and Efficacy Study on Hepatocellular Carcinoma Patients
Single Center and Exploratory Investigator-initiated Trial to Evaluate the Safety and Efficacy of Needle Guiding Robot System for Radiofrequency Ablation in Hepatocellular Carcinoma Patients
NCT03005756CI-TRIAL-00034777NGRunknownN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The needle guiding robot helps targeting of radiofrequency ablation needles by matching computed tomography images and patients' bodies. Actual insertion of needles will be performed by doctors. This study evaluates the safety and efficacy of needle targeting on patients with hepatocellular carcinoma.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Carcinoma, Hepatocellular | Hepatocellular Carcinoma | ONTOLOGY_EXACT | 0.98 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Needle guiding robot | Device | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- EXPERIMENTAL
- label
- Robot-assisted Radiofrequency Ablation
- description
- CT-guided radiofrequency ablation of hepatocellular carcinoma using needle guiding robot
- interventionNames
- Device: Needle guiding robot
Primary outcomes (1)
- measure
- Total radiation exposure (DLP, mGy*cm)
- timeFrame
- At time of radiofrequency ablation
- description
- Sum of radiation exposures measured during the radiofrequency ablation
Secondary outcomes (3)
- measure
- Number of repositioning of radiofrequency electrode
- timeFrame
- At time of radiofrequency ablation
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 19 Years
- Maximum age
- 80 Years
Show eligibility criteria text
Inclusion Criteria: * Patients with up to three Hepatocellular carcinomas (HCC) with no single HCC larger than 3 cm * Candidates for CT-guided radiofrequency ablation of HCC * Child-Pugh class A or B Exclusion Criteria: * Patients with untreatable/unmanageable coagulopathy * Patients who are allergic to CT contrast media * Patients with vascular invasion or extrahepatic metastases
References
Publications (3)
- BACKGROUNDKoethe Y, Xu S, Velusamy G, Wood BJ, Venkatesan AM. Accuracy and efficacy of percutaneous biopsy and ablation using robotic assistance under computed tomography guidance: a phantom study. Eur Radiol. 2014 Mar;24(3):723-30. doi: 10.1007/s00330-013-3056-y. Epub 2013 Nov 13. PMID 24220755
- BACKGROUNDAbdullah BJ, Yeong CH, Goh KL, Yoong BK, Ho GF, Yim CC, Kulkarni A. Robot-assisted radiofrequency ablation of primary and secondary liver tumours: early experience. Eur Radiol. 2014 Jan;24(1):79-85. doi: 10.1007/s00330-013-2979-7. Epub 2013 Aug 9. PMID 23928933
- BACKGROUNDAbdullah BJ, Yeong CH, Goh KL, Yoong BK, Ho GF, Yim CC, Kulkarni A. Robotic-assisted thermal ablation of liver tumours. Eur Radiol. 2015 Jan;25(1):246-57. doi: 10.1007/s00330-014-3391-7. Epub 2014 Sep 5. PMID 25189152