Clinical trial · Interventional
Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration Using a 22 vs 25-Gauge Needle
Endobronchial Ultrasound-guided Transbronchial Needle Aspiration Using a 22 vs 25-Gauge Needle; A Randomized Controlled Trial
NCT03004586CI-TRIAL-00059232completedN/AResults postedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The goal of this clinical research study is to compare the effectiveness of a smaller, 25-gauge needle when used in an endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) instead of a standard 22-gauge needle. The safety of the needles will also be studied.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Lung Cancer | Malignant Lung Neoplasm | CURATED_EXACT | 0.92 |
| Malignant Neoplasm of Respiratory and Intrathoracic Organ Carcinoma | Lung Neoplasm | PROBABILISTIC | 0.70 |
Interventions
Interventions (3)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| 22-Gauge Needle | Device | — | UNRESOLVED |
| 25-Gauge Needle | Device | — | UNRESOLVED |
| Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration (EBUS-TBNA) | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- EBUS-TBNA:First Using a 25-Gauge Needle Then 22-gauge Needle
- description
- Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) performed by first using a 25-gauge needle, followed by a 22-gauge needle.
- interventionNames
- Device: 25-Gauge Needle
- Device: 22-Gauge Needle
- Procedure: Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration (EBUS-TBNA)
- type
- EXPERIMENTAL
- label
- EBUS-TBNA:First Using a 22-Gauge Needle Then 25-gauge Needle
- description
- Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) performed by first using a 22-gauge needle, followed by a 25-gauge needle.
- interventionNames
- Device: 25-Gauge Needle
- Device: 22-Gauge Needle
- Procedure: Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration (EBUS-TBNA)
Primary outcomes (1)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: 1. Age 18 years or older 2. Indication for EBUS-guided needle biopsy based on suspicion of either benign or malignant disease in mediastinal or hilar lymph nodes. Exclusion Criteria: 1. Patients who are pregnant or lactating 2. Inability to give informed consent 3. Patients in which only one lymph node station is expected to be sampled by the performing clinician.
References
Publications (0)
Data not yet available
No reference posted for this study.