Clinical trial · Observational
Immunologic Signatures Following Surgery for Pancreatic Cancer
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The goal of this pilot study is to evaluate and describe the immunologic and overall outcomes of subjects who undergo routine pancreatectomy with or without irreversible electroporation (IRE) for pancreatic cancer. Immunologic markers in the blood will be measured at several time points before and after surgery to determine if surgical approach is associated with different immunologic responses. Secondary outcomes will include mortality and morbidity; operative time; blood loss and transfusion requirements; and oncologic outcomes such as: margin status, lymph node harvest, disease-free survival, and overall survival. Analysis of immune response will help the investigator determine whether to expand the pilot into a larger study.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Pancreatic Cancer | Malignant Pancreatic Neoplasm | CURATED_EXACT | 0.92 |
| Surgery | — | UNRESOLVED | — |
Interventions
Interventions (0)
Data not yet available
Design
Arms and outcomes
Arms (1)
- label
- Surgery
- description
- No intervention. Patients who undergo surgical resection of their pancreatic cancer.
Primary outcomes (1)
- measure
- immune response
- timeFrame
- preoperatively to 3 months postoperatively
- description
- proliferation of immune cells in peripheral plasma
Secondary outcomes (14)
- measure
- 90-day mortality
- timeFrame
- 90 days
- description
- death by 90 days
- measure
- surgical-site infection (SSI)
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Subject must be at least 18 years of age and at least the minimum age of majority according to applicable State or Country Law. * Subject is a suitable surgical candidate, i.e., is able to undergo general anesthesia and pancreatectomy for diagnosis of cancer * Subject is willing and able to undergo additional blood draws Exclusion Criteria: • Subject is not a suitable candidate for surgery, or surgery is unable to be completed
References
Publications (0)
Data not yet available