Clinical trial · Interventional
Motorized Spiral Colonoscopy Trial: A First Feasibility Trial
Motorized Spiral Colonoscopy Trial (MSCT): A First Feasibility Trial
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The aim of this study is to assess the feasibility and the safety of the Novel Motorized Spiral Endoscope to examine the colon. The study is conceived as proof of concept trial with the primary aim to achieve a cecal intubation rate of at least 90 % according to quality guidelines recommendations. All other clinically relevant quality parameters of standard colonoscopy will be evaluated as secondary aims comparable to our recent trial. This study represents the first clinical evaluation of using a motorized spiral assisted endoscope for examination of the colon with potential advantages for patients in terms of effectiveness and convenience of colonoscopy.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Adenoma | Adenoma | ONTOLOGY_EXACT | 0.98 |
| Colonoscopy | — | UNRESOLVED | — |
| Safety Issues | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Motorized Spiral Colonoscopy | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- EXPERIMENTAL
- label
- Motorized Spiral Colonoscopy
- description
- Motorized Spiral Colonoscopy (MSC) with the novel motorized spiral endoscope represents a new technology which offers all of the advantageous options of spiral-assisted endoscopy with a faster and less invasive approach
- interventionNames
- Procedure: Motorized Spiral Colonoscopy
Primary outcomes (1)
- measure
- Cecal intubation rate
- timeFrame
- 3 days
Secondary outcomes (10)
- measure
- Ileum intubation rate
- timeFrame
- 3 days
- measure
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Screening for colorectal neoplasia * Surveillance after previous polypectomy/endoscopic mucosal resection (EMR) * Positive results on colorectal cancer (CRC) screening tests * Evaluation of clinical symptoms of non overt gastrointestinal bleeding * Indeterminate iron-deficiency anaemia * Chronic diarrhoea * Indeterminate large-bowel symptoms requiring evaluation for colorectal disease Exclusion Criteria: * Age under 18 years * Health status American Society of Anesthesiologists classification (ASA) level ≥ 3 * Pregnancy * Known coagulopathy (INR≥2.0, Platelets \< 70/nl) * Anti-platelet agents or anticoagulants (other than aspirin) within last 7 days * History of chronic inflammatory bowel disease * Previously identified colorectal polyps/lesions with indication for endoscopic resection * Any medical contraindication to standard colonoscopy * Any prior abdominal surgery of the mid or lower gastrointestinal tract (except uncomplicated appendectomy) * Known or suspected bowel obstruction or stenosis * Known hemorrhoids 3rd degree * Suspected perforation of the GI tract * Inability to tolerate sedation for any reason * Absence of a signed informed consent
References
Publications (1)
- DERIVEDBeyna T, Schneider M, Pullmann D, Gerges C, Kandler J, Neuhaus H. Motorized spiral colonoscopy: a first single-center feasibility trial. Endoscopy. 2018 May;50(5):518-523. doi: 10.1055/s-0043-123577. Epub 2017 Dec 18. PMID 29253918