Clinical trial · Interventional
Cardiac Arrhythmias in Patients Undergoing Kidney Cancer Surgery Depending on the Anaesthesia Method
Evaluation of Cardiac Arrhythmias in Patients Undergoing Kidney Cancer Surgery Depending on the Anaesthesia Method
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This study evaluates the incidence of cardiac arrhythmias during the perioperative period in patients undergoing open kidney cancer surgery in the lateral position. All the participants will be randomly allocated to receive general (Group G) or combined epidural/general anaesthesia (Group G/E). The anaesthetic technique is standardized. The Holter monitor will be applied at the evening before the surgery, tracing continuously for a period of 24 hours (7PM-7PM)
Conditions
Conditions (4)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Anesthesia, Local | — | UNRESOLVED | — |
| Arrhythmia, Cardiac | — | UNRESOLVED | — |
| Kidney Cancer | Malignant Kidney Neoplasm | CURATED_EXACT | 0.92 |
| Surgery | — | UNRESOLVED | — |
Interventions
Interventions (5)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Bupivacaine-fentanyl | Drug | — | UNRESOLVED |
| Epidural Anaesthesia | Procedure | — | UNRESOLVED |
| General anesthesia | Procedure | — | UNRESOLVED |
| Holter ECG monitor | Device | — | UNRESOLVED |
| Open kidney cancer surgery | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- ACTIVE_COMPARATOR
- label
- General anesthesia (G)
- description
- Holter ECG monitor General anesthesia Open kidney cancer surgery
- interventionNames
- Device: Holter ECG monitor
- Procedure: Open kidney cancer surgery
- Procedure: General anesthesia
- type
- EXPERIMENTAL
- label
- Combined general/epidural (G/E)
- description
- Holter ECG monitor Epidural anesthesia General anesthesia Open kidney cancer surgery
- interventionNames
- Drug: Bupivacaine-fentanyl
- Device: Holter ECG monitor
- Procedure: Open kidney cancer surgery
- Procedure: General anesthesia
- Procedure: Epidural Anaesthesia
Primary outcomes (1)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Open renal cell carcinoma surgery, lateral position * American Society of Anesthesiologists (ASA) physical grade I-III * No history of cardiac arrhythmias * Informed consent Exclusion Criteria: * Pregnancy and breast feeding * Contraindications for epidural anesthesia * Laparoscopic or robotic surgery * Suspected difficult intubation (ex. fibroscopic) * Chest deformations * Prior cardiac/thoracic surgery * Cardiac insufficiency * abnormal ECG before the surgery
References
Publications (1)
- DERIVEDDobronska K, Jureczko L, Kowalczyk R, Dobronski P, Trzebicki J. Open kidney cancer surgery and perioperative cardiac arrhythmias. Cent European J Urol. 2020;73(4):432-439. doi: 10.5173/ceju.2020.1734. Epub 2020 Nov 2. PMID 33552568