Clinical trial · Interventional
Extended-release vs Immediate-release Metformin in PCOS Women
NCT02984722CI-TRIAL-00025048unknownN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The aim of our study is to compare the different effects of 6 months treatment with extended-release metformin and immediate-release metformin on clinical, endocrine and metabolic parameters in women affected by polycystic ovary syndrome. We also evaluate gastrointestinal disorders associated with the two different compouds.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Polycystic Ovary Syndrome | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Metformin | Drug | Metformin | ALIAS |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- 1
- description
- PCOS women treated with 1500 mg/die of extended-release metformin
- interventionNames
- Drug: Metformin
- type
- EXPERIMENTAL
- label
- 2
- description
- PCOS women treated with 1500 mg/die of immediate-release metformin
- interventionNames
- Drug: Metformin
Primary outcomes (1)
- measure
- Gastro intestinal disorders
- timeFrame
- 6 months
Secondary outcomes (10)
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
- Maximum age
- 35 Years
Show eligibility criteria text
Inclusion Criteria: * women with PCOS in accordance with Rotterdam criteria Exclusion Criteria: * pregnancy * diabetes mellitus (or impaired glucose tolerance as determined by a standard 75 gr oral glucose tolerance test) * past history of cardiovascular diseases * past history of gastro-intestinal diseases * significant liver or renal dysfunction (hypothalamic, pituitary, thiroidal or adrenal); * neoplasms.
References
Publications (0)
Data not yet available
No reference posted for this study.