Clinical trial · Interventional
Effect of Low vs Moderate-intensity Endurance Exercise on Physical Functioning Among Breast Cancer Survivors
Effect of Low-intensity Versus Moderate-intensity Endurance Exercise on Physical Functioning Among Breast Cancer Survivors: a Randomized Controlled Trial
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of this study is to evaluate the effect of two exercise programs: 1) one program will be at low intensity; 2) the other program will be at moderate intensity. One hundred forty two women who are breast cancer survivors will be recruited. Participants will be educated on a home exercise program to be performed at either low or moderate intensity, according to group assignment. Evaluations to participants will consist of function and quality of life.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Breast Neoplasms | Breast Neoplasm | ONTOLOGY_EXACT | 0.98 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Exercise Program Low Intensity | Behavioral | — | UNRESOLVED |
| Exercise Program Moderate Intensity | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Low Intensity Exercise
- description
- Participants engage in low intensity endurance exercise.
- interventionNames
- Behavioral: Exercise Program Low Intensity
- type
- EXPERIMENTAL
- label
- Moderate Intensity Exercise
- description
- Participants engage in moderate intensity endurance exercise.
- interventionNames
- Behavioral: Exercise Program Moderate Intensity
Primary outcomes (5)
- measure
- Change in Cardiovascular fitness: Six-minute walk test
- timeFrame
- At month 1 prior to intervention (pre-test); at 6-month (post-test); 6-month follow up.
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 50 Years
Show eligibility criteria text
Inclusion Criteria: 1. Fifty years of age or older 2. Be a resident of the San Juan metropolitan area of Puerto Rico (PR) 3. Diagnosed with breast cancer 4. Be classified in breast cancer stage grouping 0 to III according to the American Joint Committee on Cancer Classification of Malignant Tumors (TNM) Staging System (2013) 5. Have completed adjuvant curative therapy at least two months to 5 years prior to recruitment Exclusion Criteria: 1. Women who have contraindications to exercise, such as extreme fatigue or anemia, unstable cardiac disease; uncontrolled diabetes; uncontrolled hypertension; coagulopathies; inability to ambulate independently 2. Women with metastasis or secondary cancers 3. Women who already meet the national standard for exercise (≥ 150 minutes per week of moderate exercise).
References
Publications (1)
- DERIVEDMulero Portela AL, Colon Santaella CL, Rogers LQ, Missaghian Vissepo M. Effect of low- and moderate-intensity endurance exercise on physical functioning among breast cancer survivors: a randomized controlled trial. Support Care Cancer. 2024 Dec 21;33(1):49. doi: 10.1007/s00520-024-09100-2. PMID 39714637