Clinical trial · Observational
DAnish Nausea Study In Advanced Cancer-Epidemiology: A Danish Multicenter Trial to Investigate the Prevalence and Treatment of Nausea and/or Vomiting in Patients With Advanced Cancer.
NCT02980289CI-TRIAL-00034523completedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The study aims to investigate the prevalence and treatment of nausea and/or vomiting in patients with advanced cancer not receiving chemotherapy or irradiation.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Advanced Cancer | Malignant Neoplasm | CURATED_BROADER | 0.78 |
| Emesis | — | UNRESOLVED | — |
| Nausea | — | UNRESOLVED | — |
Interventions
Interventions (0)
Data not yet available
No intervention recorded.
Design
Arms and outcomes
Arms (1)
- label
- Patients
- description
- Patients over 18 years old with advanced cancer defined as metastatic disease, no curable treatment options. The patients may not have received chemotherapy or irradiation within 4 weeks, no operations within 2 weeks and no general anesthesia within 4 days.
Primary outcomes (1)
- measure
- 2-item nausea-score from EORTC-QLQ-C15-Pal at baseline and 1 week
- timeFrame
- From baseline and at 1 week (5-9 days)
- description
- The primary objective is to observe the effect of standard anti-emetics on change in two-item nausea-score from baseline to 24 hours.
Secondary outcomes (4)
- measure
- Nausea CAT-score from EORTC-QLQ-C15-Pal at baseline and after 1 week
- timeFrame
- 1 week (5-9 days)
- description
- Change in nausea CAT-score from baseline to 24 hours and 7 days
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: 1. Advanced cancer 2. Age ≥ 18 years 3. Ability to read and understand the forms required for the study 4. Life-expectancy more than 2 weeks. 5. Nausea score ≥ 'a little' on the extended EORTC QLQ-C15-PAL (item 9) Exclusion Criteria: 1. Surgery to the brain or abdomen within the last 2 weeks or exposure to general anesthesia within the last 4 days. 2. Chemotherapy or radiation therapy within the last 4 weeks 3. Symptoms of increased intracranial pressure or cerebral metastasis. If this is suspected, a normal MRI scan of the cerebrum is needed before inclusion 4. Radiologically confirmed ileus, or strong clinical suspicion evaluated by the study Investigator 5. Pregnancy
References
Publications (0)
Data not yet available
No reference posted for this study.