Clinical trial · Observational
Laparoscopy for Primary Cytoreductive Surgery in Advanced Ovarian Cancer
Laparoscopy for Primary Cytoreductive Surgery in Advanced Ovarian Cancer: a Prospective Validation and Comparison With Open Surgery.
NCT02980185CI-TRIAL-00024989completedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
To assess the feasibility, Residual Tumor, complication rate and survival of totally laparoscopic primary cytoreduction in carefully selected patients with Advanced Ovarian Cancer, compared with abdominal primary cytoreduction in a single-Institution, single-surgeon prospective series.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Disease-free Survival | — | UNRESOLVED | — |
| Overall Survival | — | UNRESOLVED | — |
| Residual Tumor | Neoplasm | CURATED_BROADER | 0.78 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Laparoscopic primary cytoreduction | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- label
- Laparoscopic primary cytoreduction
- description
- Patients in whom primary cytoreduction was performed using a laparoscopic approach
- interventionNames
- Procedure: Laparoscopic primary cytoreduction
- label
- Abdominal primary cytoreduction
- description
- Patients in whom primary cytoreduction was performed using an open abdominal approach
Primary outcomes (1)
- measure
- Residual tumor at the end of surgery (using the completeness of cytoreduction score)
- timeFrame
- June 2007 - July 2015
Secondary outcomes (2)
- measure
- Disease-free Survival
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- Female
Show eligibility criteria text
Inclusion Criteria: * Primary Ovarian cancer * Epithelial histotype * Stage III-IV disease Exclusion Criteria: * Anesthesiological contraindication to primary cytoreduction * Extension of disease contraindicating primary cytoreduction
References
Publications (2)
- BACKGROUNDNezhat FR, DeNoble SM, Liu CS, Cho JE, Brown DN, Chuang L, Gretz H, Saharia P. The safety and efficacy of laparoscopic surgical staging and debulking of apparent advanced stage ovarian, fallopian tube, and primary peritoneal cancers. JSLS. 2010 Apr-Jun;14(2):155-68. doi: 10.4293/108680810X12785289143990. PMID 20932362
- DERIVEDCeccaroni M, Roviglione G, Bruni F, Clarizia R, Ruffo G, Salgarello M, Peiretti M, Uccella S. Laparoscopy for primary cytoreduction with multivisceral resections in advanced ovarian cancer: prospective validation. "The times they are a-changin"? Surg Endosc. 2018 Apr;32(4):2026-2037. doi: 10.1007/s00464-017-5899-9. Epub 2017 Oct 19. PMID 29052073