Clinical trial · Observational
Perceptions of Side Effects of Cancer Chemoradiotherapy
Patient Perceptions of Side Effects of Cancer Chemoradiotherapy
NCT02978846CI-TRIAL-00035164completedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This study is asking patients who are undergoing radiation therapy with or without chemotherapy on how well they evaluate their side effects on the last day of treatment. This study is not to change health outcomes of the patients in this study. Asking patients to rank side effects in order of which ones bother them the most may help researchers identify the most troubling side effects of cancer treatment.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Malignant Neoplasm | Malignant Neoplasm | ONTOLOGY_EXACT | 0.90 |
| Side Effect | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Clinical Observation | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- Observational (side effects evaluation using cards)
- description
- Patients are shown two groups of cards on the last day of radiation treatment. Group A lists 48 physical side effects and group B lists 27 psychosocial side effects. The cards are shuffled and patients view one card at a time and select the side effects they attribute to their current treatment. Patients rank the selected cards from each group by order of severity. The top 5 cards from each group are then shuffled together and patients rank the remaining 10 cards in order of severity.
- interventionNames
- Other: Clinical Observation
Primary outcomes (1)
- measure
- Identify the most common type of side effects as perceived by patients on the last day of radiation treatment
- timeFrame
- Up to 1 year
- description
- Tables and bar charts will be used to display the 10-20 highest ranked side effects overall, by sex and concurrent chemotherapy. Descriptive statistics such as means and standard deviation will be used.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Diagnosis of cancer * Has received at least 4 consecutive weeks of definitive radiation treatment, with or without concurrent chemotherapy * Has not received greater than 4 weeks of chemotherapy prior to radiation therapy start * Ability to understand and the willingness to sign a written informed consent Exclusion Criteria: * Patients with either a central nervous system (CNS)-primary cancer or with brain metastases
References
Publications (1)
- DERIVEDWilliams PA, Cao S, Yang D, Jennelle RL. Patient-reported outcomes of the relative severity of side effects from cancer radiotherapy. Support Care Cancer. 2020 Jan;28(1):309-316. doi: 10.1007/s00520-019-04820-2. Epub 2019 May 2. PMID 31044307