Clinical trial · Interventional
Mucolytic Solution Before Upper Endoscopy
The Use of Mucolytic Solution Before Upper Endoscopy: A Randomized, Double-blinded Trial
NCT02967094CI-TRIAL-00024944unknownN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Study was designed to evaluate efficacy of mucolytic solution ingested before upper endoscopy on visibility of gastric mucosa.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Gastroscopy; Gastric Cancer | Gastric Neoplasm | ALIAS | 0.90 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Administration of mucolytic solution before upper endoscopy (Espumisan, ACC long) | Drug | — | UNRESOLVED |
| Administration of water before upper endoscopy | Drug | — | UNRESOLVED |
Design
Arms and outcomes
Arms (3)
- type
- EXPERIMENTAL
- label
- A - mucolytic solution
- description
- Mucolytic solution consisting of 100 ml of water, 100 mg of simethicon and 400 mg of N-acetylcystein administered 30 minutes prior to upper endoscopy.
- interventionNames
- Drug: Administration of mucolytic solution before upper endoscopy (Espumisan, ACC long)
- type
- NO_INTERVENTION
- label
- B - no intervention
- description
- Upper endoscopy without neither mucolytic solution nor water prior to upper endoscopy.
- type
- PLACEBO_COMPARATOR
- label
- C - water
- description
- 100 ml of water given 30 minutes prior to upper endoscopy.
- interventionNames
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * age \> 18 years * signed informed consent * diagnostic gastroscopy Exclusion Criteria: * age \< 18 years * interventional gastroscopy * known disease of the upper GI tract and/or history of surgery of GI tract * gastroscopy indicated of bleeding, dysphagia or ileus * liver cirrhosis * general anesthesia
References
Publications (1)
- DERIVEDStepan M, Falt P, Pipek B, Fojtik P, Hanousek M, Hill M, Urban O. Administration of mucolytic solution before upper endoscopy - double-blind, monocentric, randomized study. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2023 Mar;167(1):69-73. doi: 10.5507/bp.2021.038. Epub 2021 Jun 22. PMID 34158672