Clinical trial · Interventional
MS Versus NICE for Colorectal Lesions
Prospective Randomised Study Comparing Modified Sano's (MS) Classification and NBI International Colorectal Endoscopic (NICE) for Differentiating Colorectal Lesions
NCT02963207CI-TRIAL-00024799completedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
OBJECTIVE: Our study aimed to compare a recently-developed endoscopic classification with an established one for colorectal lesions in a randomised trial between 2013 and 2015.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Colorectal Neoplasms | Colorectal Neoplasm | ONTOLOGY_EXACT | 0.98 |
| Colorectal Polyp | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Modified Sano's classification | Other | — | UNRESOLVED |
| NICE classification | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Modified Sano's Classification
- description
- Modified Sano's Classification as described by Singh et al. 2013
- interventionNames
- Other: Modified Sano's classification
- type
- ACTIVE_COMPARATOR
- label
- NICE classification
- description
- NBI International Colorectal Endoscopic Classification as described by Hewett et al. 2012
- interventionNames
- Other: NICE classification
Primary outcomes (3)
- measure
- Accuracy measures in comparison to the final histopathology in regards to polyps' subtype (neoplastic versus non-neoplastic)
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Patients admitted in the Endoscopy Unit for a colonoscopy * Patients over 18 years-old * Patients or their caregivers that have understanding of the procedure and that have signed the consent form for the study Exclusion Criteria: * Patients without colorectal polyps * Patients with poor bowel preparation * Patients that do not agree with or withdraw the consent form
References
Publications (2)
- BACKGROUNDSingh R, Jayanna M, Navadgi S, Ruszkiewicz A, Saito Y, Uedo N. Narrow-band imaging with dual focus magnification in differentiating colorectal neoplasia. Dig Endosc. 2013 May;25 Suppl 2:16-20. doi: 10.1111/den.12075. PMID 23617643
- BACKGROUNDHewett DG, Kaltenbach T, Sano Y, Tanaka S, Saunders BP, Ponchon T, Soetikno R, Rex DK. Validation of a simple classification system for endoscopic diagnosis of small colorectal polyps using narrow-band imaging. Gastroenterology. 2012 Sep;143(3):599-607.e1. doi: 10.1053/j.gastro.2012.05.006. Epub 2012 May 15. PMID 22609383