Clinical trial · Interventional
Different Anesthetic Managements of Esophageal Resection and Reconstruction
The Effects of Different Anesthetic Managements on Inflammation, Oxidative Injuries, and Major Organ Complications: a Prospective Investigations on Esophageal Reconstruction and Intraoperative Shock
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Anesthetic management and fluid therapy is crucial in esophageal resection and reconstruction, which is associated with high incidence of postoperative morbidity and mortality. This study aims to investigate the effect of goal directed fluid management on the postoperative outcome of esophageal resection and reconstruction.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Anesthesia | — | UNRESOLVED | — |
| Esophagus Cancer | — | UNRESOLVED | — |
| Postoperative Complications | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Cardiac Output Maximization | Other | — | UNRESOLVED |
| Cardiac Output Normalization | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Cardiac Output Maximization
- description
- maximize stroke volume, and maintain cardiac index and stroke volume variation during the whole operation
- interventionNames
- Other: Cardiac Output Maximization
- type
- ACTIVE_COMPARATOR
- label
- Cardiac Output Normalization
- description
- keep cardiac index (CI) ≥ 2.2, and maintain CI and stroke volume variation during the whole operation
- interventionNames
- Other: Cardiac Output Normalization
Primary outcomes (1)
- measure
- Incidence of postoperative complication
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 35 Years
- Maximum age
- 65 Years
Show eligibility criteria text
Inclusion Criteria: * Patients diagnosed as esophageal cancer * Scheduled for minimally invasive esophageal resection and reconstruction Exclusion Criteria: * End-stage organ dysfunction, including heart failure, hepatic failure, renal failure * Arrhythmia * Pregnancy
References
Publications (0)
Data not yet available