Clinical trial · Interventional
Application of 3D Printing Technique in Small Pulmonary Nodule Localization
Three-Dimensional Printing of Navigational Template in Localization of Small Pulmonary Nodule: A Prospective, Randomized, Controlled, Non-inferiority Trial
NCT02952261CI-TRIAL-00036202completedN/AResults postedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The trial is to evaluate the efficacy and safety of three-dimensional printed navigational template in the clinical application of small peripheral lung nodule localization.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Lung Neoplasm | Lung Neoplasm | ONTOLOGY_EXACT | 0.98 |
| Thoracic Surgery, Video-Assisted | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| CT-guided localization | Other | — | UNRESOLVED |
| template-guided localization | Device | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- OTHER
- label
- CT-guided localization
- description
- This group of participants received conventional CT-guided lung nodule localization.
- interventionNames
- Other: CT-guided localization
- type
- EXPERIMENTAL
- label
- template-guided localization
- description
- Three-dimensional printed template was customized based on participant's computed tomography information. Participants received template-guided lung nodule localization.
- interventionNames
- Device: template-guided localization
Primary outcomes (1)
- measure
- Accuracy of Lung Nodule Localization
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 19 Years
- Maximum age
- 80 Years
Show eligibility criteria text
Inclusion Criteria: 1. Aged from 19 to 80 years 2. lesions located in peripheral lung tissue which can be removed by wedge resection 3. The maximum diameter of the lesion is no more than 20 mm. 4. Research assistant consulted with the patient's surgeon to confirm the necessity of lung nodule localization 5. Informed consent was signed voluntarily. Exclusion Criteria: 1. nodule located in the scapula region. 2. there were two or more lung nodules needed to be localized.
References
Publications (2)
- BACKGROUNDZhang L, Li M, Li Z, Kedeer X, Wang L, Fan Z, Chen C. Three-dimensional printing of navigational template in localization of pulmonary nodule: A pilot study. J Thorac Cardiovasc Surg. 2017 Dec;154(6):2113-2119.e7. doi: 10.1016/j.jtcvs.2017.08.065. Epub 2017 Sep 1. PMID 29017792
- DERIVEDZhang L, Wang L, Kadeer X, Zeyao L, Sun X, Sun W, She Y, Xie D, Li M, Zou L, Rocco G, Yang P, Chen C, Liu CC, Petersen RH, Ng CSH, Parrish S, Zhang YS, Giordano R, di Tommaso L; AME Thoracic Surgery Collaborative Group. Accuracy of a 3-Dimensionally Printed Navigational Template for Localizing Small Pulmonary Nodules: A Noninferiority Randomized Clinical Trial. JAMA Surg. 2019 Apr 1;154(4):295-303. doi: 10.1001/jamasurg.2018.4872. PMID 30586136