Clinical trial · Interventional
Effects of Acupuncture Stimulation on Systemic Inflammation
Effects of Acupuncture Stimulation on Systemic Inflammation in Patients Undergoing Video-assisted Thoracoscopic Lobectomy Surgery
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
60 ASA physical status I or II patients, aged 18-75 years old , scheduled for elective video-assisted thoracoscopic lobectomy surgery,will be randomized into 2 groups,with 30 patients in each group: 1. control group and 2. treatment group. Patients in treatment group will receive transcutaneous electrical acupoint stimulation(TEAS) during the surgery and at 6h and 24h after surgery. Patients in the control group received only TIVA general anesthesia and sham electrical stimulation. Serum from patients of both groups will be collected at before surgery, 1h and 25h after surgery, respectively. Serum levels of TNF-alpha, IL-1 beta, CXCL8, IFN gamma and IL-4 at different time points will be measured and compared between the two groups.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Nonsmall Cell Lung Cancer | Lung Non-Small Cell Carcinoma | ALIAS | 0.90 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Acupuncture stimulation | Procedure | — | UNRESOLVED |
| Sham stimulation | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- SHAM_COMPARATOR
- label
- Sham stimulation
- description
- Put the electrodes on SI3, SJ6, PC6 and LI4 without stimulation.
- interventionNames
- Procedure: Sham stimulation
- type
- EXPERIMENTAL
- label
- Treatment: Acupuncture stimulation
- description
- Stimulate the SI3, SJ6, PC6 and LI4 since 30 minutes before anesthesia induction until the end of operation. Stimulate again at above acupoints at 6 and 24h after operation, for 30 minutes each time. The stimulation frequency is 2/100Hz. The stimulation current is two to three times of the lowest current that the patient can feel.
- interventionNames
- Procedure: Acupuncture stimulation
Primary outcomes (2)
- measure
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 75 Years
Show eligibility criteria text
Inclusion Criteria: * Patients diagnosed Non-Small Cell Lung Carcinoma (NSCLC) and will have elective video-assisted thoracoscopic lobectomy surgery * ASA grade 1-2 * BMI between 18 to 31 kg/m2 Exclusion Criteria: * with a history of thoracic surgery * Unwilling to receive transcutaneous electrical acupoint stimulation * BMI ≥ 32 kg/m2 * Infection or scars at the acupoints * periphery nerve injury at the upper or lower limbs * Severe liver, renal, brain or lung disease * Drug abuse * Patients who cannot coordinate with investigators, such as dysphasia，severe infectious disease and disturbance of consciousness * Patients participating other trials
References
Publications (0)
Data not yet available