Clinical trial · Observational
TARGeted Intraoperative radioTherapy (TARGIT) Registry Database
TARGIT R: TARGeted Intraoperative radioTherapy (TARGIT) Registry Database
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This is a prospectively registered database of patients with early breast cancer who will be treated with radiotherapy during surgery. More than 2000 women have already received this treatment in clinical trials. This study will monitor the health status of women who receive this treatment outside of a clinical trial, especially those who might not have been eligible for the original clinical trials. The aim is to confirm the long-term effectiveness and safety of the technique.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Early-Stage Breast Carcinoma | Early Stage Breast Carcinoma | ONTOLOGY_EXACT | 0.98 |
Interventions
Interventions (0)
Data not yet available
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (2)
- measure
- Local tumour control (defined as no recurrent tumour in the ipsilateral breast)
- timeFrame
- Five years
- description
- Confirmation that the TARGIT technique results in an acceptably low rate of local recurrence when given outside of a randomised controlled trial.
- measure
- Adverse events related to the primary treatment of the breast cancer.
- timeFrame
- Five years
- description
- Confirmation that the TARGIT technique results in an acceptably low rate of safety events assessed by CTCAE v4.0 when given outside of a randomised controlled trial.
Secondary outcomes (1)
- measure
- Cost effectiveness
- timeFrame
- Five years
- description
- Confirmation that the TARGIT technique is cost-effective as assessed by both health related quality of life (EQ5D) and cost data.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Recommended treatment by MDT * Consent has been obtained to have patient data to be collected Exclusion Criteria: * Pregnancy (females who have a positive pregnancy test prior to surgery) * Under 18 years of age
References
Publications (0)
Data not yet available