Clinical trial · Observational
Effect of Uterine Manipulator on Recurrence and Mortality of Endometrial Cancer
Effect of Uterine Manipulator on Recurrence and Mortality of Endometrial Cancer: a Multi-centric Study
NCT02943811CI-TRIAL-00024803completedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The investigators sought to retrospectively assess whether the use of a intrauterine device to manipulate the uterus does affect the long-term oncologic outcomes of patients operated by laparoscopy for endometrial cancer
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Endometrial Cancer | Malignant Endometrial Neoplasm | CURATED_BROADER | 0.80 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| UTERINE MANIPULATOR | Device | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- label
- MANIPULATOR
- description
- Patients who were operated for endometrial cancer by laparoscopy with the use of a uterine manipulator
- interventionNames
- Device: UTERINE MANIPULATOR
- label
- NO MANIPULATOR
- description
- Patients who were operated for endometrial cancer by laparoscopy without the use of a uterine manipulator
Primary outcomes (1)
- measure
- Disease recurrence
- timeFrame
- 4 years
- description
- Relapse of disease during follow-up
Secondary outcomes (2)
- measure
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
- Maximum age
- 100 Years
Show eligibility criteria text
Inclusion Criteria: * Clinical stage I endometrial cancer * Laparoscopic operation Exclusion Criteria: * post-operative oncologic follow-up \< 12 months * extra-uterine evidence of disease
References
Publications (2)
- BACKGROUNDMarcos-Sanmartin J, Lopez Fernandez JA, Sanchez-Paya J, Pinero-Sanchez OC, Roman-Sanchez MJ, Quijada-Cazorla MA, Candela-Hidalgo MA, Martinez-Escoriza JC. Does the Type of Surgical Approach and the Use of Uterine Manipulators Influence the Disease-Free Survival and Recurrence Rates in Early-Stage Endometrial Cancer? Int J Gynecol Cancer. 2016 Nov;26(9):1722-1726. doi: 10.1097/IGC.0000000000000808. PMID 27518143
- BACKGROUNDTinelli R, Cicinelli E, Tinelli A, Bettocchi S, Angioni S, Litta P. Laparoscopic treatment of early-stage endometrial cancer with and without uterine manipulator: Our experience and review of literature. Surg Oncol. 2016 Jun;25(2):98-103. doi: 10.1016/j.suronc.2016.03.005. Epub 2016 Mar 23. PMID 27312035