Clinical trial · Interventional
Impact of Adapted Physical Activity on Cognitive Functions in Breast Cancer
Study of Impact of Adapted Physical Activity on Cognitive Functions and Quality of Life in Patients Treated for Locally Advanced Breast Cancer
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Breast cancer is the most frequent cancer in women in western countries. The improvement of therapeutic management associated to the developement of supportive care allows patient to live longer in better conditions. But several studies have showed the deleterious impact of treatment such as chemotherapy on cognition. To limit these damages, non therapeutic approaches such as Adapted Physical Activity (APA) have been developped. The goal of this study is to evaluate the benefit of APA program on cognitive functions in patients with locally advanced breast cancer.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Breast Cancer | Malignant Breast Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| delayed APA program | Other | — | UNRESOLVED |
| immediate APA program | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Immediate APA
- description
- intervention: 10 sessions of APA within the 5 weeks (2 sessions per week) following the randomization
- interventionNames
- Other: immediate APA program
- type
- ACTIVE_COMPARATOR
- label
- Delayed APA
- description
- intervention: 10 sessions of APA in 5 weeks (2 sessions per week) , 3 months after randomization
- interventionNames
- Other: delayed APA program
Primary outcomes (1)
- measure
- proportion of patient with an increase of Functional Assessment of Cancer Therapy-Cognitive Function (FACT-COG) result
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Women * More than 18 years old * Locally advanced breast cancer * Patient who undergone surgery * Cognitive complaint (FACT-COG inferior or equal to 8/16) * No metastasis at the inclusion * Patient who received adjuvant therapy by chemotherapy * Patient with a social protection * Barbizet scale Superior or equal to 3 * No neurological history * No medical contraindication to APA * Inform consent signed Exclusion Criteria: * Metastatic breast cancer * History of other cancer (in 5 years before inclusion) * Current chemotherapy or radiotherapy * Chemotherapy or radiotherapy ended for more than 6 months * Current APA program * Blood transfusion for less than 6 mois * Minimal mental score inferior to normal * Patient no able to respond to the cognitive test * Patient no able to realize APA program * Drug use * Alcohol abuse * Patient Under guardianship or curatorship or deprived of liberty
References
Publications (0)
Data not yet available