Clinical trial · Interventional
Neuromas as the Cause of Pain
Infiltration of Neuromas With Local Anesthetics to Eliminate Pain: A Double-blinded Crossover Study
NCT02930551CI-TRIAL-00037000completedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Neuromas are frequent after trauma and surgery, including amputation and can be identified by high-resolution ultrasound. The role of neuromas as the cause of neuropathic pain is uncertain. The investigators therefore wish to explore if spontaneous and evoked pain will be relieved by injection of local anesthetics near painful neuromas in subjects with peripheral nerve injury.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Neuroma | — | UNRESOLVED | — |
| Neuropathic Pain | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Isotonic Saline | Drug | — | UNRESOLVED |
| Lidocaine | Drug | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- ACTIVE_COMPARATOR
- label
- Lidocaine
- description
- Lidocaine 2 ml injection with 2% Adrenaline
- interventionNames
- Drug: Lidocaine
- type
- PLACEBO_COMPARATOR
- label
- Isotonic Saline
- description
- Isotonic Saline 2 ml Injection
- interventionNames
- Drug: Isotonic Saline
Primary outcomes (2)
- measure
- Spontaneous pain on numerical rating scale (NRS 0-10)
- timeFrame
- 15 minutes after injection
- description
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 85 Years
Show eligibility criteria text
Inclusion Criteria: * Subjects with peripheral nerve injury 3 months prior to participation Exclusion Criteria: * Severe somatic or psychiatric diseases * Other peripheral neuropathy * Lack of ability to cooperate to the clinical examination * Allergy to Lidocaine or similar analgetics
References
Publications (0)
Data not yet available
No reference posted for this study.