Clinical trial · Interventional
Advanced Endoscopic Imaging in Colonoscopy
A Prospective Randomized Clinical Trial to Assess the Utility of Advanced Endoscopic Imaging and the Impact of New Technologies on Quality in Colonic Examinations
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The aim of the study is to evaluate the usefulness of high-tech endoscopy in clinical practice. The important elements of this evaluation are: * Evaluation of the character of neoplastic lesions in the colon based on different imaging techniques * Verification of the endoscopic image with histopathologic descriptions * Establishing the type of the lesion on the basis of Kudo and NICE classifications * Comparison of the result of histopathological examination with the macroscopic type of the lesion * Determination of the most advanced lesions (MAL) * Comparison of the cecal intubation time * Evaluation of the type of anesthesia used during colonoscopy * Subjective assessment of the severity of pain according to VAS (visual analogue scale) * Comparison of the accuracy of the location of lesions on the basis of endoscopic navigation * Comparison of the total examination time * Comparison of adenoma detection rate
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Neoplasms | Neoplasm | ONTOLOGY_EXACT | 0.90 |
| Polyps | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Conventional colonoscopy (Olympus CF-H180DL) | Device | — | UNRESOLVED |
| Innovative colonoscopy (Olympus CF-HQ190L, NBI + Dual Focus) | Device | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Innovative colonoscopy
- description
- Innovative colonoscopy performed using narrow band imaging and dual focus function (NBI + Dual Focus)
- interventionNames
- Device: Innovative colonoscopy (Olympus CF-HQ190L, NBI + Dual Focus)
- type
- ACTIVE_COMPARATOR
- label
- Conventional colonoscopy
- description
- Conventional colonoscopy performed without innovative techniques assessed in this study.
- interventionNames
- Device: Conventional colonoscopy (Olympus CF-H180DL)
Primary outcomes (1)
- measure
- Diagnostic accuracy of innovative colonoscopy
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 40 Years
- Maximum age
- 65 Years
Show eligibility criteria text
Inclusion Criteria: * written informed consent * no previous abdominal surgery * no colonoscopy during last 10 years Exclusion Criteria: * age \< 40 and \> 65 years * large bowel resection in history * colonoscopy performed during last 10 years * contraindications for general anaesthesia * ASA \> IV * pregnancy * confirmed neoplastic disease * cirrhosis (Child B or C) or ascites * immunosuppressive therapy or steroids intake * malabsorption syndrome * IBD * GI neoplastic disease
References
Publications (1)
- DERIVEDBogacki P, Gach T, Krzak J, Szura M. Panoramic colonoscopy in colorectal cancer screening - a randomized controlled trial. Wideochir Inne Tech Maloinwazyjne. 2021 Jun;16(2):289-296. doi: 10.5114/wiitm.2021.103922. Epub 2021 Feb 25. PMID 34136023