Clinical trial · Observational
Optimal Initiation of Helicobacter Pylori Eradication After Endoscopic Resection for Gastric Neoplasm
Optimal Initiation of Helicobacter Pylori Eradication After Endoscopic Resection
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
After endoscopic resection (ER) of gastric tumors, eradication of Helicobacter pylori (H. pylori) infection is advised to reduce metachronous recurrence. However, few studies have addressed factors influencing H. pylori eradication rates in the aftermath of ER, and none have focused on the optimal timing of therapy to eradicate H. pylori post-ER.Therefore, the investigators will conduct to evaluate whether differences in timing of eradication therapy after ER of gastric tumors.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| H.Pylori Eradication Rate | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| eradication timing | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- label
- early eradication group
- description
- In the post-endoscopic resection period, patients were grouped by timing (i.e., initiation) of therapy to eradicate H. pylori as follows: 1) early (≤ 2 weeks), 2) late (≥ 8weeks).
- interventionNames
- Other: eradication timing
- label
- late eradication group
- description
- In the post-endoscopic resection period, patients were grouped by timing (i.e., initiation) of therapy to eradicate H. pylori as follows: 1) early (≤ 2 weeks), 2) late (≥ 8weeks).
- interventionNames
- Other: eradication timing
Primary outcomes (1)
- measure
- H. pylori eradication rate according to timing of therapeutic regimen after endoscopic resection
- timeFrame
- The success of H. pylori eradication was determined using a urea breath test conducted 13 weeks ± 5 days after ESD
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 20 Years
- Maximum age
- 90 Years
Show eligibility criteria text
Inclusion Criteria: 1. patients underwent endoscopic resection of gastric neoplasm 2. patients who diagnosed as H. pylori infection by rapid urease test Exclusion Criteria: 1. Histories of gastric surgery 2. Histories of prior H. pylori eradication therapy 3. Use of drugs affecting H. pylori positivity (proton pump inhibitor, histamine-2 receptor blocker, or antibiotics) within the preceding 2 weeks
References
Publications (1)
- DERIVEDHuh CW, Jung DH, Kim JH, Park H, Youn YH. Early versus Late Eradication of Helicobacter pylori after Endoscopic Submucosal Dissection of Gastric Neoplasms: A Prospective, Multicenter, Randomized, Controlled Study. Gut Liver. 2025 Nov 15;19(6):821-828. doi: 10.5009/gnl250004. Epub 2025 May 28. PMID 40425226