Clinical trial · Interventional
In Vivo EGFR-ECD Molecular Imaging Using [68Ga]- Labelling Anti-EGFR Affibody Molecule
Targeted Molecular Imaging of [68Ga]- Labelling Anti-EGFR Affibody Molecule in EGFR ECD in Lung Cancer Patients and Healthy Volunteers
NCT02916329CI-TRIAL-00024044unknownN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The investigators developed \[68Ga\]-labelling Anti-EGFR Affibody Molecule as a targeted molecular imaging agent for noninvasive and repeatable detecting EGFR-ECD expression status.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Molecular Imaging | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| 68Ga-NODAGA-Ac-Cys-ZEGFR:1907 | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (6)
- type
- EXPERIMENTAL
- label
- 68Ga-ZEGFR: EGFR++
- description
- Patients in this group had EGFR-activating mutant and EGFR high expression tumors and did not receive any treatment before this study.
- interventionNames
- Other: 68Ga-NODAGA-Ac-Cys-ZEGFR:1907
- type
- EXPERIMENTAL
- label
- 68Ga-ZEGFR: EGFR+
- description
- Patients in this group had EGFR-activating mutant and EGFR medium expression tumors and did not receive any treatment before this study.
- interventionNames
- Other: 68Ga-NODAGA-Ac-Cys-ZEGFR:1907
- type
- EXPERIMENTAL
- label
- 68Ga-ZEGFR: EGFR-
- description
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Advanced NSCLC * 18 years or older * A life expectancy of at least 12 weeks * Presence of a malignant lesion within the chest of at least 0.5 cm diameter as measured by computed tomography (CT) * Written informed consent Exclusion Criteria: * Claustrophobia * Pregnancy * Metal implants in the thorax
References
Publications (0)
Data not yet available
No reference posted for this study.