Clinical trial · Observational
Extracellular RNA Markers of Liver Disease and Cancer
NCT02908048CI-TRIAL-00110470terminatedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Why stopped (as posted): Ran out of funds
Summary
Brief summary (as posted)
The study will examine and evaluate the use of extracellular RNA in blood as markers for the diagnosis of liver disease or cancer, and as markers for prediction of response to treatment or recurrence of cancer after surgery
Conditions
Conditions (4)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Biliary Tract Cancer | Malignant Biliary Tract Neoplasm | ALIAS | 0.90 |
| Cirrhosis | — | UNRESOLVED | — |
| Hepatocellular Carcinoma | Hepatocellular Carcinoma | ONTOLOGY_EXACT | 0.98 |
| Liver Diseases | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Blood samples | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (4)
- label
- Hepatocellular Carcinoma
- description
- Blood samples will be collected at entry into the study and at varying intervals over a two to three year period.
- interventionNames
- Other: Blood samples
- label
- Biliary Tract Cancer
- description
- Blood samples will be collected at entry into the system and at varying intervals over a two to three year period.
- interventionNames
- Other: Blood samples
- label
- Cirrhosis
- description
- Blood samples will be collected during regular intervals over a three year period.
- interventionNames
- Other: Blood samples
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Lab results from within the previous 90 days. * Diagnosis of HCC or biliary tract cancer * Diagnosis of cirrhosis based on histology, imaging, or ultrasound. * Diagnosis of a chronic liver disease without cirrhosis. Exclusion Criteria for the HCC/biliary tract cancer group: * Prior solid organ transplant. * Previous cancer history with the last 5 years (excluding non-melanoma skin cancer), participation in a treatment trial for HCC Exclusion criteria for the cirrhosis and chronic liver disease groups: * Prior solid organ transplant. * Previous or current cancer history within the past 5 years (excluding non-melanoma skin cancer).
References
Publications (0)
Data not yet available
No reference posted for this study.