Clinical trial · Interventional
The Application of Personalized Titanium Plate in the Bone Tumors Around the Knee
Personalized Titanium Plate Improves Clinical Outcome in Microwave Ablation of Bone Tumors Around the Knee
NCT02901782CI-TRIAL-00025937completedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Microwave ablation of bone tumors is time-consuming and usually results in postoperative fractures. Hence the investigators designed and fabricated a titanium plate customized to the patient's bone structures for fixation after the removal of tumorous tissue, to improve the clinical outcomes of microwave ablation.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Bone Tumors | Bone Neoplasm | ALIAS | 0.90 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Personalized titanium plate | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- EXPERIMENTAL
- label
- Personalized titanium plate
- description
- Ten males and two females with a mean age of 22.8 years were recruited. They all had bone tumor around the knee.
- interventionNames
- Procedure: Personalized titanium plate
Primary outcomes (3)
- measure
- Musculoskeletal Tumor Society score
- timeFrame
- An average of 29 months
- measure
- Mean maximum flexion of the knee
- timeFrame
- An average of 29 months
- measure
- The six degrees of freedom of the gait
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 5 Years
- Maximum age
- 80 Years
Show eligibility criteria text
Inclusion Criteria: 1. Clinical diagnosis of primary malignant bone tumors in the distal femur or proximal tibia according to the preoperative biopsy. 2. Malignant soft tissue tumor invading distal femur or proximal tibia. 3. The patients have the opportunity of limb salvage and treatment of microwave-induced hyperthermia in situ and reconstruction with internal fixation. Exclusion Criteria: 1. Distant metastasis. 2. Benign tumor. 3. Metastatic tumor around the knee. 4. No indication of limb salvage. 5. Malignant soft tissue tumor without bone invasion. 6. Recrudescent tumors.
References
Publications (0)
Data not yet available
No reference posted for this study.