Clinical trial · Interventional
Mindfulness-based Stress Reduction (MBSR) Program Combined With Endurance Exercise Training: a Help in Treatment for Breast Cancer
Effect of a Mindfulness-based Stress Reduction (MBSR) Program Combined With Endurance Exercise Training: a Help to Improve Exercise Capacity and Quality of Life in Breast Cancer
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Integrative approaches to promote wellness and reduce the distress associated with cancer are considered as essential components of cancer care. In case, exercise training has been shown to produce many positive physiological and psychological benefits. Mindfulness-based stress reduction program shows similar beneficial effects, and especially in emotional distress management. The aim of the study is to examine the cumulative effect of an 8 week-exercise-training program combined with an MBSR program on cardio-respiratory fitness and quality of life in women with breast cancer. These effects are thought to be mediated in part through changes in underlying brain processes, that investigators will be put in light. Through telomerase activity, oxidative stress, mitochondrial respiration and blood cytokine level measurements, investigators could expect to better understand the effect of these combined training in breast cancer.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Breast Cancer | Malignant Breast Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (7)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Both interventions together | Other | — | UNRESOLVED |
| Cerebral IRMf | Other | — | UNRESOLVED |
| Endurance exercise training | Other | — | UNRESOLVED |
| Mindfulness-based-stress-reduction | Other | — | UNRESOLVED |
| Quality of life (questionnaires) | Other | — | UNRESOLVED |
| Telomerase activity on a blood sample | Genetic | — | UNRESOLVED |
| Vo2max measurements | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (4)
- type
- PLACEBO_COMPARATOR
- label
- Control patients with no intervention
- description
- group without intervention
- interventionNames
- Other: Vo2max measurements
- Genetic: Telomerase activity on a blood sample
- Other: Quality of life (questionnaires)
- Other: Cerebral IRMf
- type
- EXPERIMENTAL
- label
- Endurance training program (8 weeks) group
- description
- only physical training group
- interventionNames
- Other: Endurance exercise training
- Other: Vo2max measurements
- Genetic: Telomerase activity on a blood sample
- Other: Quality of life (questionnaires)
- Other: Cerebral IRMf
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
- Maximum age
- 65 Years
Show eligibility criteria text
Inclusion Criteria: * Breast cancer * Having completed the chemotherapy period * Undergoing radiotherapy and/or hormono therapy Exclusion Criteria: * Regular physical activity higher than 4 hours per week. * Any disease cardiac, respiratory, neurological or articular disease, which counteract the muscular training )
References
Publications (1)
- RESULTSibeoni J, Manolios E, Mathe J, Feka V, Vinez MM, Lonsdorfer-Wolf E, Bloch JG, Bayle F, Meunier JP, Revah-Levy A, Verneuil L. The experience of a program combining two complementary therapies for women with breast cancer: An IPSE qualitative study. PLoS One. 2023 Aug 17;18(8):e0285617. doi: 10.1371/journal.pone.0285617. eCollection 2023. PMID 37590246