Clinical trial · Interventional
Back Pain Prevention in Multiple Myeloma Using an External Spinal Brace
Back Pain Prevention in Multiple Myeloma Using an External Spinal Brace - a Feasibility Study
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Consenting patients with multiple myeloma (MM) will be randomly allocated to receive either standard medical treatment (chemotherapy, radiotherapy, pain-killing medication) alone or standard medical treatment plus a brace. Patients will be regularly evaluated in research clinics; the results data will inform the design of a full trial. Information will be collected to inform a list of requirements a centre needs to have in place to run an RCT of these interventions.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Multiple Myeloma | Multiple Myeloma | CURATED_EXACT | 0.92 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Standard care | Other | — | UNRESOLVED |
| thoracolumbosacral orthosis or cervicothoracolumbar orthosis | Device | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- OTHER
- label
- Standard care + brace
- description
- Spinal brace (thoracolumbosacral orthosis or cervico-thoraco-lumbar orthosis) to be fitted to the participant in addition to receiving standard of care treatment which can include radiotherapy, chemotherapy or surgery including vertebral augmentation and also medication including bisphosphonates
- interventionNames
- Device: thoracolumbosacral orthosis or cervicothoracolumbar orthosis
- Other: Standard care
- type
- OTHER
- label
- Standard care
- description
- Participant will receive standard of care treatment which can include radiotherapy, chemotherapy or surgery including vertebral augmentation and also medication including bisphosphonates
- interventionNames
- Other: Standard care
Primary outcomes (6)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Adults with MM * Myeloma infiltration in the spine confirmed by radiological evidence * MM-related back pain * Can attend for the whole follow up period Exclusion Criteria: * Presenting with cord compression and neurological deficit requiring urgent decompression and intervention * Chronic pain syndrome * Language barrier that cannot be overcome using translation services * Unwilling or unable to give informed consent * Painful VCFs at the lumbosacral junction, L4 to Sacrum, where application of brace is not possible. Not suitable for treatment with a brace e.g. pregnancy
References
Publications (0)
Data not yet available