Clinical trial · Interventional
Osteoarticular Tumor Characterization by Advanced Imaging
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose is to compare and evaluate multiple functional imaging methods (perfusion, diffusion, spectroscopy) for initial benign/malignant characterization of osteoarticular tumors and to determine which method or which association of methods could improve non invasive tissue characterization. Secondary purposes are: * to determine a possible correlation between some parameters and the histological grade (FNCLCC) * to suggest a coherent diagnostic imaging approach for osteoarticular tumors. The ancillary study will enroll patients needing radiological tumor follow-up. The purpose is to identify tools for evaluation of tumor activity and therapeutic response before modification of morpho-volumetric data.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Bone Tumor | Bone Neoplasm | ALIAS | 0.90 |
| Soft Tissue Tumor | Soft Tissue Neoplasm | ALIAS | 0.90 |
Interventions
Interventions (3)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| CT scan | Other | — | UNRESOLVED |
| Ecography | Other | — | UNRESOLVED |
| MRI | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- EXPERIMENTAL
- label
- Patients with bone or peripheral soft-tissue tumor
- interventionNames
- Other: Ecography
- Other: CT scan
- Other: MRI
Primary outcomes (19)
- measure
- Contrast enhancement in echography: yes or no
- timeFrame
- baseline
- measure
- Contrast enhancement curve (absent, slow or fast) in echography
- timeFrame
- baseline
- measure
- Maximal intensity of enhancement peak in echography
- timeFrame
- baseline
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * patients examined for initial assessment of bone or peripheral soft-tissue primitive tumor * patients with normal awareness level * patients having signed informed consent Exclusion Criteria: * pregnant women * persons deprived of liberty * persons under legal protection or unable to give informed consent * persons in life-threatening emergency * allergy to Sonovue, iodinated contrast media or gadolinium chelates * risk of pregnancy * breastfeeding women * acute coronary syndrome or unstable ischemic cardiopathy (ban on injection of contrast agent for CT scan) * renal failure (ban on injection of contrast agent for MRI and CT scan) * contraindication to MRI
References
Publications (1)
- DERIVEDRibeiro GJ, Gillet R, Hossu G, Trinh JM, Euxibie E, Sirveaux F, Blum A, Teixeira PAG. Solitary bone tumor imaging reporting and data system (BTI-RADS): initial assessment of a systematic imaging evaluation and comprehensive reporting method. Eur Radiol. 2021 Oct;31(10):7637-7652. doi: 10.1007/s00330-021-07745-9. Epub 2021 Mar 25. PMID 33765161